Sentences with phrase «small molecules called»

According to a new report from the researchers at Intermountain Medical Center Heart Institute, a connection has been made between small molecules called microRNAS and the threat of an imminent heart attack.

Researchers focused on two species of bacteria that break up dietary fibers from food into small molecules called short - chain fatty acids.

By definition, «proteins are actually chains of small molecules called amino acids.

Paulaitis says «the novel concepts put forth in this study, of investigating small molecules called microRNAs to see what they can tell us about mitochondria disorders in cells of the retina, hold great promise of providing new insights into how age - related macular degeneration develops, after which new treatments can be designed to save or improve vision.»

That DNA is packaged up by winding around histones (middle), and small molecules called polyamides are able to bind to that DNA, unlike most natural cellular proteins.

A new study that included researchers from Norway, the University of Washington, the University of California San Diego and The University of Texas Health Science Center at San Antonio (now called UT Health San Antonio ™) found that dozens of small molecules called metabolites are altered in this disease.

So to garner enough iron to survive, bacteria secrete small molecules called siderophores to seek out iron in the environment and bring it back into the cell through siderophore - specific receptors.

Small molecules called metabolites mediate a cell's survival, and metabolite production is fine - tuned by genes that indirectly sense metabolite levels.

The molecule, miR - 34a, belongs to a family of small molecules called microRNAs (miRNAs) that serve as brakes to help regulate how much of a protein is made, which in turn, determines how cells respond.

Living cells, whether they are healthy or cancerous, produce small molecules called metabolites.

In a study involving researchers from the Queensland Brain Institute, scientists have shed light on the role that small molecules called microRNAs play in early brain development.

The RNA molecule is constructed of smaller molecules called nucleotides.

They focused on the p75NTR receptor, a protein which is found on the tips of peripheral neurons and known to bind a small molecule called NGF (for nerve growth factor).

The activity of the latter protein is known to be blocked by a small molecule called Nutlin - 3.

Scientists already have a drug that can curb Brd4's actions — a small molecule called JQ1 that prevents Brd4 from binding to chromatin.

The new drug, a small molecule called anle138b, blocks these pores from moving ions in and out of nerve cells.

Proteins are made of smaller molecules called amino acids, which combine to form modules.

Published in the August 2015 issue of Nature Medicine, the new findings show that a small molecule called N1 - methylnicotinamide prevents metabolic complications caused by a high - fat diet.

In addition to adding the genes for glucaric acid production, the researchers engineered each cell to produce a protein that synthesizes a small molecule called AHL.

By using a small molecule called 2 - bromo - palmitate (2BP) that inhibits these palmitate - adding enzymes, the researchers surmise that cancer patients might be able to one day make their cells more sensitive to cancer - fighting EGFR inhibitors.

The target is a small molecule called homocysteine.

They then add a small molecule called TRAP to the living cell, which finds and fits into the tag like two pieces in a puzzle.

«In our previous work, we found that a drug - like small molecule called JQ1 can prevent the development of heart failure in mouse models when administered at the very onset of the disease.

They also support the existence of four related subtypes based on the patterns of DNA methylation — a chemical reaction in which a small molecule called a methyl group is added to DNA, changing the activity of individual genes.

The researchers used a small molecule called 2 - deoxyglucose, or 2DG, to block glucose metabolism and produce a ketogenic state in rats.

Not exact matches

They then sound the alarm by producing small hormone - like molecules called cytokines and chemokines.

The new research, published recently as two separate studies in ACS Central Science and the Journal of the American Chemical Society, demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.

He worked on the organic synthesis of molecules able to recognize and bind with other, smaller molecules, a phenomenon called molecular recognition, which had won Donald J. Cram, Jean - Marie Lehn, and Charles J. Pedersen the Nobel Prize in chemistry in 1987.

To use fructose for energy, the body needs to convert it into another type of simple sugar called glucose or into other smaller molecules.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

The technique examines the small molecules, or metabolites, within cells, bio-fluids, tissue, or organisms and their interactions within the larger system, called a metabolome.

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

Our guide is a small, «elegant» molecule called carbon disulfide — a compound that is a key ingredient in the making of viscose (better known as rayon) and is also insidiously toxic, having devastated the minds and bodies.

Ribosomes decipher the sequence of an mRNA with the help of small cloverleaf shaped molecules called «transfer» or tRNA.

Researchers knew that cells could ingest some molecules and break them down completely inside small vesicles called lysosomes, but none of the products was transported back to the surface of the cell.

But a string of recent discoveries indicates that a class of RNA molecules called small RNAs are actually in charge of many cellular functions.

These effector proteins and other small molecules in their spit cause the root cell to forego normal processes and create a huge feeding site called a syncytium.

The researchers behind the new study, from Winston - Salem State University in the US and Universiti Malaysia Sarawak in Malaysia, have found that adding similar, but smaller polycationic molecules onto a new kind of material called carbon nanodots makes them even better at killing drug - resistant bacteria.

«We call it mimicry,» says Sean Brady, director of Rockefeller University's Laboratory of Genetically Encoded Small Molecules, where the research was conducted.

By studying the regulation of the clock proteins called Period (PER) and Cryptochrome (CRY)-- proteins that are thought to be involved with metabolism — St. John and Doyle were able to model the mechanisms of two small - molecule drugs — Longdaysin and KL0001 — that regulate the expression of the clock proteins.

In previous studies, Anderson and Langer showed they could block multiple genes with small doses of siRNA by wrapping the RNA in fatlike molecules called lipidoids.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

In order to fit inside cells, DNA is wrapped around small protein spindles, forming strings of molecules called nucleosomes.

The researchers realized that the segmental (also called structural) relaxation in the case of polymers presents the relaxation of only a small part of the molecule.

The fine walls of small blood vessels, called capillaries, function as semi-per-meable membranes: water molecules can pass through them.

New hope for improved detection comes in the form of small RNA molecules called microRNAs.

The majority of drugs that humans use to treat the variety of ailments we suffer are so - called «small molecules.»

The sodium channel lies on the surface of the nerve and muscle cells and is composed of a large molecule called the α - subunit, together with smaller β - subunit molecules.

The patterns of a type of molecule that influences epigenetic inheritance, called small noncoding RNA, differed between the two groups, as did methylation patterns in the sperm DNA in the two groups, the team reports today in Cell Metabolism.

It contains two essential parts, a small RNA molecule called a microRNA (miRNA) which guides RISC to its mRNA target; and a much larger component into which the guide RNA fits, a protein called Argonaute, which, Joshua - Tor showed in 2004, actually performs the «slicing up» of the mRNA.