Sentences with phrase «small molecules like»

They have created the first porous liquid, specially designed of cage - like molecules sized to capture small molecules like methane or carbon dioxide, but too large to be filled by the liquid solvent in which they are dissolved.

The emissivity and absorptivity of small molecules like CO2 and H2O follow the structure of their line absorption spectrum.

When he moved back to Tokyo in 1977 to the lab of Yasuhiro Anraku, Ohsumi continued with his new study subject, but worked on transport systems that moved small molecules like amino acids and calcium into and out of the yeast version of the lysosome (idiosyncratically known by yeast biologists as the vacuole — which means «empty space»).

In 2009, scientists at IBM used an AFM with a CO2 molecule adsorbed on the tip, and using the interaction of this molecule with carbon atoms, they were able to resolve with high detail the chemical structure of small molecules like pentacene.

«This special protein family is characterized by molecular pockets that can take in small molecules like retinoic acid, which is a metabolite of vitamin A,» explains first author Karin Hufnagl.

The smart gel could provide structural rigidity in organs such as the lungs, and can contain small molecules like water or drugs to be transported in the body and released.

Interestingly, the dominant model for the mechanism by which a small molecule like a drug fits into the active site of a disease - promoting enzyme and modulates its activity is that of a «lock and key».

While tearing apart even a small molecule like hydrogen may seem difficult enough, controlling the oxidation to create an energy - efficient reaction is even more challenging.

Not exact matches

They then sound the alarm by producing small hormone - like molecules called cytokines and chemokines.

Some things, like atoms and molecules, can not be seen because they are too small to be seen; but we can perceive them indirectly through electron microscopes and other such instruments.

Hitherto, in the eyes of a Science too much accustomed to reconstruct the world on one spatial axis extending in a line from the infinitely small to the infinitely great, the larger molecules of organic chemistry, and still more the living cellular composites, have existed without any defined position, like wandering stars, in the general scheme of cosmic elements.

A small proportion of links between molecules in a polymer are permanent, allowing the material to act like a spring, snapping back to its original form when stretched and released, like a piece of rubber.

«We have discovered a small molecule compound that shows a profound and prolonged effect on autism - like social deficits without obvious side effects, while many currently used compounds for treating a variety of psychiatric diseases have failed to exhibit the therapeutic efficacy for this core symptom of autism,» said Zhen Yan, PhD, professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, and senior author on the paper.

MRIs work by tapping into an astonishing phenomenon: When placed in a powerful magnetic field, the hydrogen atoms in water molecules behave like small bar magnets.

At the Gladstone, cardiovascular scientist Robert Mahley, working with a team including neuroscientist Yadong Huang, has identified small «corrector» molecules that modify the structure of ApoE4 protein to one more like that of ApoE3, thereby reducing abnormal fragmentation.

Still eager to make an MIS - like contraceptive for all women that is cheap and easy to use, perhaps as a pill, the researchers are searching libraries of small molecules to find one that mimics the action of MIS.

Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug - like molecules and the amino acids of proteins vary so much in their chemistry.

A microRNA, or miRNA, like miR - 182 is a small non-coding RNA molecule, which means, rather than actually producing proteins like regular DNA, it helps regulate protein production.

We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.

«Small molecules are perhaps more affordable as treatments and can hit things like this ion channel switch, TRPM7,» said researcher Michael Schappe, a graduate student in Desai's lab.

While small amounts of materials like zinc or silicon are required to produce thin film devices, Cadien says the costs are not insignificant — they can come in at $ 500 or $ 600 per gram and the current processes are wasteful, dosing surfaces with anywhere from 100 to 10,000 times the molecules required.

When newly hatched majors were injected with molecules that increased the number of small chemical groups attached to their DNA's protein scaffolding, they behaved like minors.

A machine in University of Illinois chemistry professor Martin Burke's lab assembles complex small molecules out of simple chemical building blocks, like a 3 - D printer on the molecular level.

Small molecules also are key elements in technologies like solar cells and LEDs.

«I was certain that it would be a small molecule, like sex pheromones in sea anemones or something along those lines.

Chemists at the University of Illinois, led by chemistry professor and medical doctor Martin D. Burke, built the machine to assemble complex small molecules at the click of a mouse, like a 3 - D printer at the molecular level.

This small protein molecule contains a loop which fits, like a key in a lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.

Simultaneously, cryoprotectants that are made up of smaller molecules such as ethylene glycol or glycerol are able to permeate the cell so it doesn't shrink up like a raisin.

«Sponge - like materials capture, store, and release essential small molecules.»

Certain ligases, like Fbxl3, can be targeted with small molecules.

A new class of experimental drug - like small molecules is showing great promise in targeting a brain enzyme to prevent early memory loss in Alzheimer's disease, according to Northwestern Medicine ® research.

Saladino and Di Mauro's work suggested that the first, small RNA molecules were most likely to come together in a water - free environment — like a formamide - rich lagoon.

The research team looked at metabolites, very small molecules produced by the body that include things like sugars, peptides, amino acids, and lipids.

DNA methylation is an epigenetic process in which small molecules — methyl groups - are added to genes and fine - tune the gene's activity, like a dimmer switch.

Anderson and Valerie Grum - Tokars, a junior structural biologist on the team, developed a three - dimensional structure of human p38 MAPK, enabling the chemists to design and synthesize novel drug - like small molecules that would disable it.

Rather, the work of folding is done by much smaller water molecules, which surround proteins and push and pull at them to make them fold a certain way in fractions of a second, like scores of tiny origami artists folding a giant sheet of paper at blazingly fast speeds.

«If we could design a small molecule inhibitor that would look like heme - iron but would actually clog up a key metabolic pathway in bacteria, we may be able to get around the problem of antibiotic resistance,» suggests Dr. Mason, who adds that he and Dr. Justice plan to use the new five - year NIH grant to further studies of just such an inhibitor.

Today in PLOS Pathogens, scientists report that they've designed small molecules to target a particularly vulnerable region of hemagglutinin, one of the two proteins that jut from the viral surface like a flower.

They are stable like small molecules and potent and selective like antibodies.

Sphingomyelinases like nSMase2 play a normal role in the cell's metabolism by breaking down fatty molecules into smaller components that cells use for every day functions.

Small peptides have the benefits of small molecule drugs, like aspirin, and large antibody therapies, like rituximab, with fewer drawbSmall peptides have the benefits of small molecule drugs, like aspirin, and large antibody therapies, like rituximab, with fewer drawbsmall molecule drugs, like aspirin, and large antibody therapies, like rituximab, with fewer drawbacks.

Like infinitesimally small Lego blocks, the nucleic acids that make up RNA connect to each other in very specific ways, which force RNA molecules to twist and loop into a variety of complicated 3D structures.

That's the surface site on the smallpox virus that we'd like to dock a small molecule into,» Hubbard explains.

He is an unquestioned leader in separation science, an important branch of analytical chemistry, who is particularly known for his studies of certain separation methods like micellar electrokinetic capillary chromatography, a useful technique for analyzing a wide variety of small molecules.

Good vibrations bring true nanotunes Researchers from the University of California, Berkeley, announced this week that they have built by far the smallest fully functioning radio receiver, made from a single carbon nanotube, a long chicken wire — like molecule.

The synthesis of this small sugar molecule was really like a total synthetic project.

Like children running through a crowd, smaller molecules of DNA move faster, and the size distribution of DNA fragments can be determined.

They then add a small molecule called TRAP to the living cell, which finds and fits into the tag like two pieces in a puzzle.

Side chains are essentially small molecules of different shapes, sizes and chemical natures attached to the longer lipid - like peptoids.

Regenerative medicine small molecule therapies offer many advantages over other therapeutic approaches including reduced complexity, ease of administration, ready reversibility, fewer regulatory hurdles and the absence of ethical concerns like those that have challenged the stem cell field.