Sentences with phrase «small number of diseases»

Not exact matches

And much of the reason its creators felt confident enough to invest all that time, money, and effort — given the small number of patients who might eventually use the medicine — can be traced to the Orphan Drug Act, a 1983 federal law that gave those who develop meds for uncommon diseases longer periods of marketing exclusivity and other financial incentives.

However, because of the small numbers, the association between exclusive breastfeeding until the age of 6 months and the risks of infectious diseases was not statistically significant when compared separately with the group of never - breastfed infants.

Newborn Screen / Metabolic Panel: A blood test done by a small prick to the heel, this test checks baby for a number of potential diseases and disorders that require fast treatment to ensure normal development.

New numbers released today by the Centers for Disease Control and Prevention indicate that a very small but slightly growing number of women are making the same choice that Jacobs did.

The number of infants receiving mixed feeding was too small (table 1) to estimate precisely its effect on diarrhoeal disease, and for further analysis they were combined either with exclusive breast milk or with formula.

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

Though still quite small, the number of home births is increasing — according to the Centers for Disease Control, it grew 29 percent between 2004 and 2009, to 29,650.

«One in 11 Americans has diabetes, and in the last 20 years, the number of adults diagnosed with diabetes has more than tripled,» said Oneida County Executive Anthony J. Picente Jr. «Making small, healthy changes to our diets and lifestyle as we age can go a long way toward preventing the onset of this terrible disease, which is the seventh leading cause of death in the United States.»

But in March, Lichun Tang of China's Beijing Proteome Research Center and colleagues reported using CRISPR / Cas9 to correct disease - causing mutations in a small number of viable human embryos.

«We expected to find that the majority of the animals would have normal airways, with only a small number actually affected with the disease, but that was not the case.»

But even preventing a small number of bites could have a huge impact because a female mosquito must engorge herself with a blood meal at least twice to transmit a disease such as malaria or dengue — once to contract the disease, and again to pass it along.

At time of writing, the virus had not become more severe, causing mild disease in most sufferers but making a small number — probably less than 1 per cent — extremely ill.

With such a limited breeding population, even a small number of deaths from disease can be the difference between the survival of a population or extinction.»

The disease is generally pretty mild — on par with flu — but health workers have recently found that a small number of patients seem to go on to develop an autoimmune disorder that can cause nerve damage and paralysis called Guillain — Barré syndrome.

The actual disparity in number of cases between the two groups was small, with 129 lung cancers in all, and the trial wasn't set up to study that disease.

Although surgery that is confined to removing just a small tumor (loco - regional treatment) is generally considered to be low risk, we have previously demonstrated that the proportion of patients who develop postoperative complications strongly increases with age and increasing numbers of other diseases or conditions that they may have.

A sleep deficiency of even a small degree can disrupt our lives in a number of ways — from a setback in daily routine to bringing about or exacerbating existing chronic diseases,» said Andrew N. Carr, Ph.D., Clinical Scientist and study co-author, Procter & Gamble.

Limitations of the study include the small numbers of people participating in NHANES who were identified as having a diagnosis of celiac disease and as adhering to a gluten - free diet without celiac disease.

And finally, once vaccinations are used, it is much harder for a country to show that it's disease free; the virus could be lurking in a small number of animals.

The most dangerous and virulent pathogens, like the Ebola virus, kill their victims too quickly, so an infected person is able to spread the disease to only a relatively small number of people before succumbing.

SAN DIEGO — A small number of people maintain razor - sharp memories into their 90s, despite having brains chock - full of the plaques and tangles linked to Alzheimer's disease.

A small but growing number of studies now suggest that air pollutants may play a role in diseases of the gut.

In 2013, India's National Vector Borne Diseases Control Program reported that the country had experienced an annual average of 20,474 dengue cases and 132 dengue - related deaths since 2007, but infectious disease experts believe those official numbers likely reflect only a small fraction of actual cases.

«However, only a smaller number of these individuals will develop the most severe form of this disease known as nonalcoholic steatohepatitis or NASH.»

Dr Jeremy Thomas, a consultant pathologist at the Western General Hospital, Edinburgh, UK, told the European Breast Cancer Conference that although the majority of women with DCIS received the correct surgery for their disease, large numbers of women were undergoing mastectomy for DCIS either as a result of failed breast conservation surgery or for tumors that turned out to be smaller than 20 mm in diameter and therefore should normally have had a lumpectomy rather than a mastectomy.

While these findings support the importance of neonatal HBV vaccination, the small number of cases of primary liver cancer and other liver diseases observed during the 30 - year follow up, the length of follow - up, and the availability of incomplete data on seroprevalence all limit the accuracy of these findings.

But if even a small number of mutant mitochondria are retained after the transfer — a common occurrence — they can outcompete healthy mitochondria in a child's cells and potentially cause the disease the therapy was designed to avoid, experiments suggest.

His group showed that a small number of stem - cell like CD8 T cells - called «memory» cells - were enough to produce and repeatedly replenish all of the T - effector cells needed to fight the disease.

A reduction in the number of these cells impairs vascular stability, and leads to cerebral small vessel disease.

Now, a study in the journal Brain describes what could be considered a direct «aquarium - to - bedside» approach, taking a drug discovered in a genetic zebrafish model of epilepsy and testing it, with promising results, in a small number of children with the disease.

Even though cancers account for a relatively small share of all disease in developing countries, the actual number of cases is greater than in the industrialised world because of the larger populations, says Indraneel Mittra, an oncologist at the Tata Memorial Centre (TMC) in Bombay.

This method will be useful when the death risk of a novel infectious disease has to be quantified using data from small numbers of patients during the course of an outbreak, providing information on which age groups to minimize exposure in hospitals, nursing homes and daycare facilities.

A small number of mice were likely already carrying the genes that protect against heavy metals or infectious diseases.

«Lithium, long used in mental health as a highly effective mood stabiliser, has been on the radar as a potential disease modifying treatment for Alzheimer's disease with positive evidence from preclinical studies and a number of small clinical trials.

We are one of a small number of centers participating in the Children's Interstitial Lung Disease (ChILD) research network.

But genetic variants in a small number of devils may let them avoid the disease.

While the study has a number of limitations — its small sample size for one and the fact that things like disease status were self - reported — the researchers had enough information to develop a genetic risk score for smokers.

Q: Last year you helped propose a smaller consortium that investigates a number of neurological diseases.

Although these studies were limited to small patient numbers, given the rarity of this disease, PD - 1 pathway blockade seems to have clinical efficacy in mucosal melanoma, with a tolerable safety profile.

Characteristic neuropathological findings were focal depletion of diffuse and neuritic plaques, but not of amyloid angiopathy, and the presence of small numbers of extremely dense (collapsed) plaques surrounded by active microglia, and multinucleated giant cells filled with dense Abeta42 and Abeta40, in addition to severe small cerebral blood vessel disease and multiple cortical hemorrhages.

The high selectivity, and the potency with which some of these receptors promote flavivirus infection, suggest only a small number of receptors might be effectively targeted to treat these diseases.

Data national registries for rare diseases: The introduction of national registries of therapy - area specific patient data across the NHS in England would see the production of meaningful datasets, especially beneficial for rare immunological diseases where patient numbers may be very small.

More recently, the approach has produced lasting remissions for a small number of patients with a common disease: ulcerative colitis.

Most of these variants are benign (having no effect on health), but a small number of variants are pathogenic (related to disease).

The small number of events could be considered another limitation; however, the present study was sufficiently powered for detection of the moderately large effect sizes observed for the key diet - disease associations.

http://www.biomedcentral.com/1741-7015/12/86 I asked Lara to provide the studies on which she is basing her blanket statement that gluten is linked to dementia when, based on what I have seen, gluten may be linked to dementia in the small number of people suffering from celiac disease.

Furthermore, there is also little question that the vast majority of conversations, seminars and published papers on the subject have addressed gut microflora purely in terms of its role in GI health, particularly in reference to the ever increasing number of patients who present with issues such as irritable bowel syndrome (IBS), small intestinal bacterial overgrowth (SIBO), and inflammatory bowel disease.

Adaptogens are a small number of plants from around the world with the ability to help the body restore balance and resist disease.

A number of small, controlled trials and case studies have tested the impact of yoga for those with spinal cord disease (myelopathy), traumatic brain injury, Guillain - Barre syndrome, amyotrophic lateral sclerosis (ALS), peripheral and diabetic neuropathies, adrenomyeloneuropathy, neurocardiogenic syncope, and other neurological anomalies.

Piperine also interferes with inflammatory signaling mechanisms and inhibits pro-inflammatory cytokines, which are small proteins secreted by some cells and linked with a number of degenerative diseases.