Sentences with phrase «small number of mice»

A small number of mice were likely already carrying the genes that protect against heavy metals or infectious diseases.

But this potential treatment has only been studied in a small number of mice.

2006 Shinya Yamanaka identifies and activates a small number of mouse genes in the cells of connective tissue, showing they can be reprogrammed to behave like immature stem cells.

Not exact matches

He recently vindicated this bit of common sense by giving a number of people either a mouse, a touchscreen, a joystick or a gaze interface to use and then racing them against each other to find and select a small target.

The average number of eggs for genetically modified mice (knockout mice) obtained using previous methods of superovulation induction is about 20 but in reality the number is often much smaller, about 10 or less.

By allowing a large number of ovulation ovum from a small number of female mice, it makes it easier to perform IVF and embryo transfers.

Later, when these mice were weaned onto a solid food diet, large numbers of pTreg cells in the small intestine emerged rapidly within a few weeks.

When comparing the numbers of cardiac stem cells in previously infected adult mice with uninfected ones, the researchers found significantly smaller numbers in the infected mice.

The mice seem to develop normally when only one copy of the gene is removed, but microscopic inspection reveals a number of small «gaps,» or disorganized regions of tissue (on the scale of a few nanometers) on their aortas, the largest artery in their bodies.

Quantification of single - fiber CSA revealed a leftward shift of the single - fiber area histogram in both EDL and TA muscles from IL - 15Rα — KO mice, indicating a greater number of smaller - sized muscle fibers (Figure 6, B and F).

(B) The single - fiber area histogram was shifted to the left, indicating a greater number of smaller - sized muscle fibers in the EDL muscles from IL - 15Ra — KO mice.

This is likely true for two reasons; 1) there would not have been much time for a large number of chromosomal rearrangements to occur between these early ancestral human and mouse genomes, 2) and that since divergence with the boreoeutherian ancestor the human genome has undergone only a small number of chromosomal rearrangements meaning that many human telomeric regions are ancestral [58, 73].

Secondly, the mouse genome is significantly smaller than the human genome, making it possible to detect a large number of lineage - specific deletion events [17, 19].

Only a small number of these interventions — Calorie Restriction, Methionine Restriction, Growth Hormone Knockout, IGF - 1 and Insulin Signalling Manipulation — have actually been shown to extend maximum lifespan in normal, healthy mice.

Note that I'm omitting a number of studies that show only small (less than 10 %) increases in maximum mouse life span, and also leaving out some work in progress that looks likely to enhance life span.

In it, the team transferred a small number of iNKT cells lacking Tet2 / 3 from mutant mice into adult mice with a robust immune system.

To sidestep the shortcomings of currently used cancer models, the Salk team harnessed the power of lentiviral vectors to infect nondividing as well as dividing cells and ferry activated oncogenes into a small number of cells in adult, fully immunocompetent mice.

Space for housing limited numbers of small animal species other than mice is also available upon request.

In the most recent assembly of the reference mouse genome (GRCm38) over 1,200 genes are annotated as coding for ORs and around 530 for VRs with a smaller number of TAAR and FPR genes.

Presumably they used this small number of cells in order to ensure that some mice would not develop tumors during the 39 day experiment.