They said that requiring hospitals to obtain authorization before including patient information in the directory would cause harm to many patients» needs in an effort to serve the needs of
the small number of patients who may not want their information to be included.
It's won the endorsement from
the small number of patients who've tried it — but that's not the market that the Frog team needs to convince.
And much of the reason its creators felt confident enough to invest all that time, money, and effort — given
the small number of patients who might eventually use the medicine — can be traced to the Orphan Drug Act, a 1983 federal law that gave those who develop meds for uncommon diseases longer periods of marketing exclusivity and other financial incentives.
Not exact matches
David Magnus, PhD, director
of the Stanford Center for Biomedical Ethics and professor
of medicine and
of biomedical ethics, said those concerns resonate beyond treating SMA
patients,
who represent a relatively
small group
of people, because competition is fierce for resources to treat
patients with any
number of illnesses for which new and more expensive treatments are emerging.
If a bacterial population can become antibiotic - resistant even when only a
small number of individuals have the appropriate genetic mutations, doctors
who collect and analyze
small bacterial specimens from
patients may underestimate just how resistant the infection is as a whole, Collins notes.
In
patients who have undergone chemotherapy and radiation, a
small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.
Although surgery that is confined to removing just a
small tumor (loco - regional treatment) is generally considered to be low risk, we have previously demonstrated that the proportion
of patients who develop postoperative complications strongly increases with age and increasing
numbers of other diseases or conditions that they may have.
The
small number of patients and the lack
of controls means that the study is not definitive, but it casts significant doubt on the effectiveness
of the hormone in children
who make normal levels
of growth hormone, he says.
By combining two or more
of these outcomes to create a single category, you can say it helped «A and B» even if it only helped A and not B. For example, although there was no statistically significant effect from tPA in the NINDS trial on the
number of patients who died, there was a
small decrease in disability for those
who survived.
There are a
small number of unscrupulous actors
who have seized on the clinical promise
of regenerative medicine, while exploiting the uncertainty, in order to make deceptive, and sometimes corrupt, assurances to
patients based on unproven and, in some cases, dangerously dubious products.
«This may be a technique that will help a
small number of migraine
patients who have responded to Botox, but it's certainly not a procedure for generally treating migraines,» says Dr. Kunkel,
who was not involved in the new study.
Furthermore, there is also little question that the vast majority
of conversations, seminars and published papers on the subject have addressed gut microflora purely in terms
of its role in GI health, particularly in reference to the ever increasing
number of patients who present with issues such as irritable bowel syndrome (IBS),
small intestinal bacterial overgrowth (SIBO), and inflammatory bowel disease.
Drugs are tested by the people
who manufacture them, in poorly designed trials, on hopelessly
small numbers of weird, unrepresentative
patients, and analysed using techniques which are flawed by design, in such a way that they exaggerate the benefits
of treatments.
In a
small number of cases,
patients who have suffered spinal cord injuries are able, with treatment, possibly surgery, and physical therapy, to regain their productive lives and regain their independence.