Sentences with phrase «small number of trials»

First, the effect sizes are smaller both in absolute terms and in comparison to effect sizes reported elsewhere — for example, in the UK, the National Institute for Health and Clinical Excellence reported effects of 1.7 for waiting list versus trauma focused psychological therapies and 1.18 for other active interventions for PTSD.1 Second, there are problems with the small number of trials in key areas (for example, TAU / WL n = 5), with the combining of different outcomes from the same study in the meta - analysis and the failure to consider clinical as opposed to statistical significance.

Fact: «Only a small number of trials employ placebos as a means of measuring a treatment's effectiveness,» says Williams.

Due to heterogeneity and to the small number of trials in each subgroup, we would advise caution when interpreting this result (Analysis 2.1).

«We're planning to build and test ultra high - speed broadband networks in a small number of trial locations across the United States,» says Google on its officail blog.

The main consequence was that confidence intervals were slightly wider, because of the smaller number of trials in the analysis.

Not exact matches

And it doesn't really do what it's supposed to: When Sprout conducted clinical trials, women only reported a small increase in the number of times they had satisfying sex — around one additional time per month.

Kirra Cheers, a photographer from Brooklyn, recently set out to document her trials and tribulations using Tinder, a wildly popular app that allows users to approve or deny potential mates based on a small number of pictures and a short bio.

Although Lu - PSMA - 617 put up good numbers in its small single - arm study, it still needs to outperform a physician's choice of approved treatments in a much larger global trial.

«The church will become small and will have to start afresh more or less from the beginning... As the number of her adherents diminishes... she will lose many of her social privileges... It will be hard going for the Church, for the process of crystallisation and clarification will cost her much valuable energy... But when the trial of this sifting is past, a great power will flow from a more spiritualised and simplified Church... And so it seems certain to me that the Church is facing very hard times.

Although further research is still needed, a number of smaller trials have suggested benefits in the weight loss and metabolism departments.

In meta - analyses with a large number of trials, as is the case in this review, there is a strong possibility that a large number of small and possibly poor quality trials will have a substantial influence on the result.

The HYPO - RT - PC trial, a randomized multi-institutional phase III trial in Scandinavia, was designed to assess outcomes from highly accelerated extreme hypofractionation, which is delivered in smaller number of high doses — seven fractions of 6.1 Gy each in this study.

The actual disparity in number of cases between the two groups was small, with 129 lung cancers in all, and the trial wasn't set up to study that disease.

However, Richard Casey, chairman of Scios Nova, the health care company in Mountain View, California, that is making the ANP for the trial, warns that the numbers involved in these earlier trials were too small to be statistically significant.

The reliably high percentage of those who develop viremia following exposure to this challenge virus is another advantage — when most or all volunteers develop viremia or other signs of infection, clinical trials can enroll relatively small numbers of people but still achieve answers to such questions as whether a candidate vaccine protects against infection, she noted.

«Previous studies suggest that reducing heart fat is feasible through weight loss or weight management, but these studies only looked at small numbers of people and there have been no clinical trials linking cardiovascular outcomes with heart fat changes due to weight management interventions.

The study was the first randomized - controlled trial to examine the potential benefits of the low fat diet on the management of MS.. The study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures of MS.. But while the number of trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies of the diet.

Two years ago, the Office of the Gene Technology Regulator granted CSIRO permission to test the variety in a short - term trial in a small number of volunteers.

This trial also looked at the effects of corticosteroids on HIV - positive people, but the small number of included participants meant that the review authors were unsure if the benefits in terms of a reduction of death was preserved in this group of participants.

By combining two or more of these outcomes to create a single category, you can say it helped «A and B» even if it only helped A and not B. For example, although there was no statistically significant effect from tPA in the NINDS trial on the number of patients who died, there was a small decrease in disability for those who survived.

Although these platforms can be used successfully for small - scale expansion of hMSCs, other platforms will be required to generate the quantity of cells required to support the increasing number of clinical trials utilizing hMSCs and the subsequent large - scale production.

«Lithium, long used in mental health as a highly effective mood stabiliser, has been on the radar as a potential disease modifying treatment for Alzheimer's disease with positive evidence from preclinical studies and a number of small clinical trials.

In the first trial (Neurology 2007; 68:51 — 55), 12 weeks of phenylbutyrate treatment produced no beneficial effects, although the small number and relatively large age range of the patients may have hidden a modest effect.

The therapy did appear to be reasonably safe: nearly all of the relatively small number of adverse events that occurred during the course of the trial were mild; the six moderate - severity adverse events and the one severe event (a case of neutropenia) were judged to be unrelated to the treatment.

Although the trial was relatively small in terms of the number of patients, it was unusually rigorous in the methods used to analyze heart metabolism, according to Gropler.

A number of small, controlled trials and case studies have tested the impact of yoga for those with spinal cord disease (myelopathy), traumatic brain injury, Guillain - Barre syndrome, amyotrophic lateral sclerosis (ALS), peripheral and diabetic neuropathies, adrenomyeloneuropathy, neurocardiogenic syncope, and other neurological anomalies.

There's a free ad easy to start with trial giving you access to just a small number of profiles you can look at, but for a low fee you can expand your dating horizons and find out more about drop dead gorgeous Russian singles who are interested in dating.

States can vet vendors, making them start slow, on a trial basis, with small numbers of students to ultimately prove themselves worthy of making it onto a state - approved vendor list.

«The jurisdictions who are continuing with that trial have committed to work closely with officials in terms of technological issues to make sure any and all issues are resolved to their satisfaction so the small number of schools participating in the trial can have absolute confidence that it will work and be successful this year.»

The scoping study enabled us to trial an approach in a small number of schools engaged with Greenhouse Sports.

A: According to Brad Carl, associate director and researcher at the Value - Added Research Center at UW - Madison, Utah and New Hampshire in recent years were allowed to provide multiple tests on a trial basis for a small number of school districts.

So, there are a number of trials, albeit much smaller than this EEF trial, which suggest that a Lesson Study approach can have significant, positive impact on student outcomes, but only when the content is of high quality.

It's that kind of fact — knowing that most of the things we're trying probably are not working — that gives you a sense of urgency around increasing the number of trials, rather than what the federal government strategy has been: to fund a few very expensive, very high - quality studies of a smaller number of interventions.

However, food trials only last for up to six months and normally include a small number of dogs that have to make it through the trial in good health.

Today's vaccines are thoroughly tested, and undergo numerous safety trials, but problems can arise in a small number of pets.

The problem is normally a small n, because trials cost money and it is easier for the NIH and others to fund a large number of poor studies than a smaller number of very good studies.

By the way, I think the reason the cardiovascular problems were not clearly revealed in clinical trials was that the relatively limited number of patients was too small to provide conclusive statistical evidence of an association.

Drugs are tested by the people who manufacture them, in poorly designed trials, on hopelessly small numbers of weird, unrepresentative patients, and analysed using techniques which are flawed by design, in such a way that they exaggerate the benefits of treatments.

However, the number of cases, which actually go to trial and which result in such multiple damage awards is relatively small.

(That is, introduce the system on a trial / test basis to a small number of users for feedback and debugging.)

The eventual trials have involved relatively small numbers of accused facing only the most serious charges.

Only a relatively small number of personal injury cases will proceed to the trial phase.

Still, an extremely small number of cases end up requiring a trial.

Only a very small number of personal injury or medical negligence claims proceed to trial.

A small number of state libraries in each include trial - level opinions.

Successfully advocating for life sciences industry clients in high - profile litigation matters, we have one of the most experienced Class Actions teams in Canada and are among a small number of Canadian firms with notable success at trial and on dispositive applications and motions.

Notwithstanding the small number of the First Nation inhabitants at the time of contact (estimated to be 400), and notwithstanding the fact that the First Nation was semi-nomadic, the Chief Justice agreed with the trial judge that those three requirements had been made out.

[217] Special Rapporteur Martin Scheinin wrote in his October 2009 report that, while there had been «a small number of cases where police officers have been subject to investigations and trial following torture complaints,» he was «troubled that complaints against SSI officers in this regard have produced no results,» and «gravely concerned» by information that terrorist suspects subjected to detention by SSI officers were at particular risk of torture.

The trial judge in Carter found that an absolute prohibition on assisted suicide promotes a small number of wrongful deaths of vulnerable persons by compelling people to end their lives sooner than necessary to do if they were able to receive assistance and found that an exception to the prohibition would likely to reduce the number of wrongful deaths.

The trial, which seems to only be available right now to a small number of users, lets you buy and sell bitcoin directly in the app.