Sentences with phrase «small number of tumor»

There are billions of red blood cells, tens of thousands of white blood cells, and, perhaps, only a small number of tumor cells floating among them.

«Hodgkin lymphoma is unusual among cancers in that it consists of a small number of tumor cells in a sea of inflammatory cells and immune system cells, including T cells that don't work very effectively.»

«Even when an entire tumor has been removed, it is common for a small number of tumor cells to remain behind.

Not exact matches

Even before treatment, cancer patients in the study had a small number of infection - and tumor - fighting T cells that target these unusual proteins, the researchers found.

SURVIVAL GEAR Some genetic variants may have allowed a small number of Tasmanian devils to withstand a deadly contagious facial tumor that has killed up to 95 percent of them in some locales.

Our job now is to figure out how to make immunotherapy effective against those tumors with small numbers of mutations.

And a small number of glioblastoma patients do not have CMV in their tumors.

Although surgery that is confined to removing just a small tumor (loco - regional treatment) is generally considered to be low risk, we have previously demonstrated that the proportion of patients who develop postoperative complications strongly increases with age and increasing numbers of other diseases or conditions that they may have.

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

«Safety thus far is likely a consequence of both the relatively small number of engineered macrophages that are injected and their sequestration into the tumors, away from most healthy cells,» Discher said.

Dr Jeremy Thomas, a consultant pathologist at the Western General Hospital, Edinburgh, UK, told the European Breast Cancer Conference that although the majority of women with DCIS received the correct surgery for their disease, large numbers of women were undergoing mastectomy for DCIS either as a result of failed breast conservation surgery or for tumors that turned out to be smaller than 20 mm in diameter and therefore should normally have had a lumpectomy rather than a mastectomy.

The total number of women who had mastectomies, including those for whom mastectomy was the first course of action as well as those who had failed breast conservation, was 2,479; of these, 510 (21 %) had mastectomies for tumors smaller than 20 mm in diameter, which would normally have been better treated with a lumpectomy.

Previously, genetic counselors tested a small number of genes sequentially based on family profile and tumor analysis until the culprit was identified.

While circulating tumor DNA tests targeting a smaller set of cancer genes are already available for use in routine practice to guide care, by covering a much larger number of cancer genes, this high - intensity sequencing approach may enable development of future tests for early detection of cancer.

But scientists have struggled for years to harness the small number of T cells, the immune system's first line of defense, that are thought to fight these tumors.

However, about 10 percent of them are common across multiple cancers, suggesting that a relatively small number of therapies targeting these core dependencies might each hold promise for combatting several tumors.

Offspring that inherited the triplicated genes and the genetic susceptibility to cancer had only half the number of intestinal tumors as their cancer - prone parents, and the tumors that did develop were smaller, the team reports in the 3 January issue of Nature.

Max S. Wicha, M.D., has received a $ 6.5 million Outstanding Investigator Award to study cancer stem cells, the small number of cells within a tumor that fuel its growth and spread.

Vescor, advised by its scientific founders White and Kimmelman, whose research has shown inhibition of autophagy can dramatically impact tumor growth in pre-clinical models, will develop small molecule inhibitors of a number of protein targets at critical nodes of the autophagy cascade, perform investigational new drug (IND) enabling studies, and move these into clinical development.

«But we know that tumors generally develop from a single cell or a small number of cells of a specific cell type, which is one of the major determinants of the characteristics of tumor cells,» explains postdoctoral researcher and co-author Dinorah Friedmann - Morvinski.

This is to accommodate small variants that occur at sites of copy number variation as well as in samples that are not pure: for example, due to tumor heterogeneity or sample mosaicism.

Identifying cancer stem cells, the small number of cells in a tumor believed to fuel its growth and spread

In tumor samples, where we frequently encounter variants with a very small allele frequency due to contamination with normal tissue, copy number variation, and tumor heterogeneity, high coverage is essential for accurate detection of these variants with high power.

Because of small sample size, the changes in tumor - initiating cell number were not significant (P > 0.05), but these data are supportive of the in vitro findings and suggest that hypoxia may have a positive effect on the tumor - initiating cell population in ER - α — positive breast cancers and a negative effect in ER - α — negative tumors.

This includes identifying pancreatic cancer stem cells, the small number of cells within a tumor that fuel its growth and spread.

And another one in rodents with lung cancer published in Science Translational Medicine in 2014 found that normal doses of vitamin E and smaller doses of acetylcysteine, an antioxidant supplement, appeared to lead to a three-fold increase in the number of tumors and caused them to be more aggressive.

This early onset suggested to Al that the number of predisposing events in these pediatric tumors must be quite small.

Due to the small number of cells injected, it takes at least two weeks before tumors are detectable in size (normally they would be visible in ten days).

Presumably they used this small number of cells in order to ensure that some mice would not develop tumors during the 39 day experiment.

Generally speaking, there are a small number of life - threatening tumors that can spread in the body, a large number of masses that cause damage inside the mouth, and a lot of swellings that are caused by inflammation and can look like other masses.

Neutered dogs have many health benefits, including a reduction in testicular tumors, fewer prostate related diseases, a reduction of perianal tumors, and a smaller number of hernias.