Sentences with phrase «small numbers of cells»

Despite this, only small numbers of cells are dividing at any one time, so the treatment is not helpful in all cases.

The Vijayanand lab has developed a number of genomics (transcriptomic, single - cell and epigenomic) and immunological assays to enable research with small numbers of cells and small - volume clinical samples.

First of all, early clinical studies of MSCs involved small numbers of cells manufactured for a small numbers of patients.

The team had to create new, highly sensitive ways to detect epigenetic marks in such small numbers of cells.

Using a new method, the scientists therefore isolated T cells specifically programmed to target the CMV virus from the blood of the donor and transferred small numbers of these cells to the patients.

That summer, President George W. Bush had approved federal funding for human ES - cell research, but only for a small number of cell lines that had already been created.

The eyeblink conditioning is stored in a small number of cells in a particular region of the cerebellum.»

«A small number of cells can cause so much trouble.

«Our work indicates that a small number of these cells can have a big impact,» says physiologist James Kirkland, one of the study's leaders.

In this way, the effect of vaccines or drugs (for example) can be tested: the more effective the active ingredient is, the smaller the number of cells that are destroyed by the viruses and the lower the measured resistance change will be.

By whatever means they are infused into the body, such vectors seem to reach and alter the DNA in only a frustratingly small number of cells.

The phenomenon is called microchimerism, a condition in which a small number of cells from two individuals coexist in one body.

Dr Byers said: «The small number of cells that show high levels of BCR - ABL may not be detectable through bulk analysis of large samples.

Max S. Wicha, M.D., has received a $ 6.5 million Outstanding Investigator Award to study cancer stem cells, the small number of cells within a tumor that fuel its growth and spread.

But a small number of cells, known as stem cells, remain uncommitted even as they spawn more specialized progeny.

«But we know that tumors generally develop from a single cell or a small number of cells of a specific cell type, which is one of the major determinants of the characteristics of tumor cells,» explains postdoctoral researcher and co-author Dinorah Friedmann - Morvinski.

To sidestep the shortcomings of currently used cancer models, the Salk team harnessed the power of lentiviral vectors to infect nondividing as well as dividing cells and ferry activated oncogenes into a small number of cells in adult, fully immunocompetent mice.

A novel study from researchers at Karolinska Institutet shows that by using so called random sequence labels, working as barcodes for tracing genetically altered cells, during CRISPR / Cas9 gene knock - outs it is possible to generate more comprehensive data from a smaller number of cells.

Identifying cancer stem cells, the small number of cells in a tumor believed to fuel its growth and spread

Diseases of the retina may offer an early test bed for hiPSC - derived cells, in the form of retinal pigmented epithelium, given the relative isolation of the tissue, and the small number of cells required [14].

This BaF3 phe116 almost completely fails to proliferate and activate STATs in response to IL - 9.15 However, upon prolonged culture with IL - 9, a small number of cells manage to survive and even proliferate, allowing an IL -9-dependent cell line (BaF3 phe116 / 9) to be selected.14 In contrast to parental BaF3 phe116 cells, those IL -9-selected cells could progress to autonomous cells (BaF3 Aut) after a second selection step in the absence of cytokine.

This includes identifying pancreatic cancer stem cells, the small number of cells within a tumor that fuel its growth and spread.

Due to the small number of cells injected, it takes at least two weeks before tumors are detectable in size (normally they would be visible in ten days).

This is an unusually small number of cells.

Presumably they used this small number of cells in order to ensure that some mice would not develop tumors during the 39 day experiment.

A very small number of cells in our verbal mind is very resourceful in tapping into our insecurities, doubts and anxieties, which results in negative self talk and mental loops of doom and gloom.

In this test, a veterinarian will insert a needle into an area of concern (an enlarged lymph node, enlarged kidney, thickened region of intestine, or fluid present within the chest) and remove a small number of cells.

Not exact matches

Despite the careful words of President Bush that this campaign will be long and difficult, there's too much belief that these operations can be localized to a small number of places, when the reality is that this cancer is metastasized to countless cells.

C - section deliveries generally yield an even smaller number of usable cells, since the collection usually can't happen until after the mother's uterus has been sewn up.

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

In 2014, Christiano and other CUMC researchers identified the immune cells responsible for destroying hair follicles in people with alopecia areata and tested an FDA - approved drug that led to complete hair regrowth in a small number of patients.

He wants to raid a fund for workers compensation, with the promise of reforming the entire system, and raise a small number of fees, including higher fines for texting or using a cell phone while driving.

Mishra's team focused on a neurotransmitter called brain natriuretic peptide (BNP), which is expressed in a small number of sensory nerve cells or neurons.

Frankencell J. Craig Venter's attempt to create an artificial cell containing the smallest possible number of essential genes.

Even before treatment, cancer patients in the study had a small number of infection - and tumor - fighting T cells that target these unusual proteins, the researchers found.

«Even when an entire tumor has been removed, it is common for a small number of tumor cells to remain behind.

The suggestion is that a small number of such cells within tumours may be the precursors to the other cancer cells in those tumours.

The researchers found that aggressive LUAD cells expressed a number of proteins that allow them to persist outside the lungs in small numbers.

Magnetospirillum cells contain a number of small particles of magnetite (Fe3O4), each approx. 45 nanometers wide.

(Previously, scientists had used CRISPR / Cas9 to repair mutations that affect smaller numbers of people with Duchenne, and in cell types that weren't necessarily clinically relevant.)

The Duke researchers who made this discovery say it may help explain how a relatively small number of genes can create the dazzling array of different cell types found in human brains and the nervous systems in other animals.

In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

Initially, it claimed to concentrate small numbers of fetal cells from the woman's blood.

The survey is small, but it does suggest there is something rotten in the state of stem cells: a worrying number of respondents admitted knowing about fraud or unethical behaviour.

«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.

Nonetheless, if a small number of inactive chlamydia cells passed from groom to bride, the infection could have became active in its new host.

«Hodgkin lymphoma is unusual among cancers in that it consists of a small number of tumor cells in a sea of inflammatory cells and immune system cells, including T cells that don't work very effectively.»

The latter can be primed in tissue culture by providing small numbers of dendritic cells.

Associate Professor Rika Numano explained, «The W / O droplet electroporation technique has several advantages over conventional transfection techniques: small cell number required, as low as 1000 cells; small amount of DNA required, which makes it applicable for various cell types including neural cells; and changeable genome DNA.

The small numbers and large sizes of brain cells in sea slugs make the animals ideal for brain research.