Sentences with phrase «small numbers of patients with»

Guideline authors noted, however, that the evidence for the recommendations is weak, since many of the studies had relatively small numbers of patients with similar types of epilepsy and were conducted at only one institution, so the results may not be generalizable to everyone with epilepsy.

While cautioning that the quantity of evidence was less - than - optimal and that the studies were qualitatively limited by the methods used to measure sodium intake, the small number of patients with health outcomes of interest in some of the studies, and other methodological constraints, the committee concluded that:

More recently, the approach has produced lasting remissions for a small number of patients with a common disease: ulcerative colitis.

Not exact matches

In 2014, Christiano and other CUMC researchers identified the immune cells responsible for destroying hair follicles in people with alopecia areata and tested an FDA - approved drug that led to complete hair regrowth in a small number of patients.

Plus, the researchers said they were left with inconclusive results because of the small number of patients enrolled.

David Magnus, PhD, director of the Stanford Center for Biomedical Ethics and professor of medicine and of biomedical ethics, said those concerns resonate beyond treating SMA patients, who represent a relatively small group of people, because competition is fierce for resources to treat patients with any number of illnesses for which new and more expensive treatments are emerging.

It was based on small numbers of patients — including just seven treated with PSR.

The disease is generally pretty mild — on par with flu — but health workers have recently found that a small number of patients seem to go on to develop an autoimmune disorder that can cause nerve damage and paralysis called Guillain — Barré syndrome.

«Medical cannabinoids should normally only be considered in the small handful of conditions with adequate evidence and only after a patient has tried of number of standard therapies,» said Allan.

Although surgery that is confined to removing just a small tumor (loco - regional treatment) is generally considered to be low risk, we have previously demonstrated that the proportion of patients who develop postoperative complications strongly increases with age and increasing numbers of other diseases or conditions that they may have.

The number of Hispanic patients in the hospitalization database with this diagnosis was extremely small.

While still controversial and performed at a small number of medical centers around the world, face transplantation has become an option for carefully selected patients with full or partial destruction of the facial tissues.

«We look for activity of our molecules in phase 2, and on numerous occasions we generate statistically significant data with relatively small numbers of patients, which gives us reasonable confidence that the program will be successful in phase 3 with a larger group of patients.

The overall in - hospital complication rate significantly decreased in patients without a comorbidity, or with a small number of comorbidities, for spinal fusion and TKR; and remained stable in those without a comorbidity, or with a small number of comorbidities, for THR in the 80 and older patient group.

Current treatments include transplanting patients with donor HSC, which is a potential cure for SCD, but due to the serious risks of rejection, only a small number of patients have undergone this procedure and it is usually restricted to children with severe symptoms.

Additionally, viral suppression was 11 percent higher at sites with a smaller number of patients and 13 percent higher at sites with fewer patients having an undetectable viral load at the beginning of the study.

The MIT researchers, along with their collaborators at MGH and other hospitals, were interested in taking advantage of the vast numbers of patient scans, which would allow them to learn much more than can be gleaned from smaller studies that produce higher - quality scans.

«However, this is an early study with a small number of patients — these results need to be confirmed with larger studies.»

But with the very small number of patients we've treated to date, our data are only suggestive.»

While there have been attempts to estimate real - time death risks during epidemics, such statistical models require data from large numbers of patients in the order of thousands and therefore could not be applied to the 2015 MERS epidemic in the Republic of Korea with small patient numbers.

To date, no links between the small number of patients infected with the mutated virus have been found and the mutation does not appear to spread.

(D) The average number of somatic hypermutations in the pandemic H1N1 patient plasmablast variable region genes compared with primary IgG plasmablast responses to vaccinia (small pox) or the anthrax vaccine, or after at least 4 boosters with the anthrax vaccine.

Researchers from UCL and Swansea have been investigating the results of autopsies from a small number of retired professional footballers with dementia in an effort to determine whether their brains showed distinct damage compared to other typical dementia patients.

Lung cancer treatment is an evolving field of science, currently there are several pathways under investigation as a possible treatment target.1 - 3 Targeted treatment is currently considered to be more efficient compared to the non-specific cytotoxic drugs, however; the small number of patients identified with mutations, limit the application of these drugs.

Although these studies were limited to small patient numbers, given the rarity of this disease, PD - 1 pathway blockade seems to have clinical efficacy in mucosal melanoma, with a tolerable safety profile.

In the coming months a small number of patients will be transplanted with fetal cells in Lund, Sweden and Cambridge, UK.

Outlier - based identification of copy number variations using targeted resequencing in a small cohort of patients with tetralogy of fallot

Gene therapy is currently offered for a small number of immunodeficiency conditions, but with further research it is hoped that the therapy can be offered to more patients in the coming years.

For example, pneumonitis, which a small number of patients on checkpoint inhibitor immunotherapy may experience, can cause some of the same symptoms as a bacterial respiratory infection, but should be treated with steroids instead of antibiotics.

Furthermore, there is also little question that the vast majority of conversations, seminars and published papers on the subject have addressed gut microflora purely in terms of its role in GI health, particularly in reference to the ever increasing number of patients who present with issues such as irritable bowel syndrome (IBS), small intestinal bacterial overgrowth (SIBO), and inflammatory bowel disease.

It is at present unknown whether an optimal balance between safety and efficacy can be achieved with the combination therapy of GH and IGF - I, since this combination has been evaluated in only a small number of patient populations and in studies of a relatively short duration.

This procedure is appropriate for a large number of small animal patients, including those presenting with chronic cystitis, pollakiuria, hematuria, stranguria, incontinence, trauma, calculi, and abnormal radiographs.

We expect veterinarians as well as cat and small dog owners around the country will be pleased since Comfortis, with its excellent efficacy, can now be used in a larger number of patients.»

In a small number of cases, patients who have suffered spinal cord injuries are able, with treatment, possibly surgery, and physical therapy, to regain their productive lives and regain their independence.

Only a small number of patients are diagnosed with schizophrenia.

While many people go to A&E with abdominal pain, only a small number of those patients have appendicitis.

Studies were generally small (mean number of patients = 35) and of variable methodological quality, with only five reporting blinding of outcome assessors to treatment allocation, and in some cases with high loss to follow - up.