Not exact matches
Small - animal imaging has become an important research tool for
preclinical studies of infectious diseases, according to senior author Thomas M. Bocan, Ph.D., of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).
The Pilot Bioproduction Facility headed by Dr. Kenneth H. Eckels, produced
small batches of vaccine candidates that were used for the
preclinical studies and is currently manufacturing a vaccine lot for use in initial human clinical
studies.
«Lithium, long used in mental health as a highly effective mood stabiliser, has been on the radar as a potential disease modifying treatment for Alzheimer's disease with positive evidence from
preclinical studies and a number of
small clinical trials.
Evaluating the efficacy of repurposed
small molecule inhibitors in treating filariasis using
preclinical and clinical
studies
«The findings of this
preclinical study contribute significantly to our understanding of SMA and provide further evidence suggesting that our strategy to upregulate SMN with
small molecules could be effective,» said Loren Eng, President of the SMA Foundation.
DG041 is a novel, first - in - class, orally - administered
small molecule which has been shown in
preclinical studies to be a selective and potent antagonist of the EP3 receptor for prostaglandin E2 (PGE2), inhibiting human platelet aggregation in a dose - dependent manner.