Sentences with phrase «small subset of cells»

Instead, a very small number of neurons specifically activated by learning show an expansion of structure that's both surprisingly extensive — there's a dramatic increase in the size and complexity of the affected neurons — and yet highly restricted to a small subset of cells.

Could Cas9 - DOG be developed soon to allow genome modification only in a small subset of cells?

Rather, each tumor contains a small subset of cells with stem cell - like capacities that are responsible for initiating and sustaining tumor growth, while the bulk of the tumor cells lacks this ability.

Second, the AAV preps generally used for gene editing are low titre, and are therefore able to infect only a small subset of the cells used in a given experiment.

Not exact matches

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

While most fat cells in the human body store energy, everyone has a small subset of brown fat cells that do the opposite — burn energy and generate heat.

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

Some of the first evidence for cancer stem cells came from studies of leukemia in the 1990s, which showed that only a small subset of the cancerous blood cells could propagate the disease in mice.

Indeed, when Blanpain and his colleagues examined mice with squamous cell carcinoma, a malignant outgrowth of the papilloma, they found that most of the cells were actively dividing, not just a small subset of stem - cell - like cells.

It suggests that at the root of any cancer there is a small subset of cancer cells that are solely responsible for driving the growth and evolution of a patient's cancer.

In the gut, a special subset of Treg cells, called peripheral Treg (pTreg) cells, exists in both the small and large intestine.

The IL - 2 receptor α subunit, CD25 is commonly expressed in T - regulatory (Treg) cells and a small subset of Reed - Sternberg cells in Hodgkin's Lymphoma (HL).

Now, researchers have found that a very small subset of anti-viral immune cells, transplanted along with a donor's blood stem cells, could be enough to fight and even prevent the disease caused by CMV, in research conducted in mice and published Jan 16th in the Journal of Immunology.

First, researchers found a pigment called melanopsin in a small subset of retinal ganglion cells (RGCs) in the eyes of rats.

But only a small subset — 5 % — of heart patients are suitable candidates for stem cell injections, said Amit Patel of the University of Pittsburgh, Pennsylvania.

Metastatic colonization is a highly inefficient process that only a small subset of disseminated tumor cells accomplish (Nguyen et al., 2009).

Smaller subsets of T cells are reactive toward various nonpeptidic ligands associated with nonpolymorphic MHC class - Ib (MHC - Ib) molecules.

After 15 days, a subset of cells expressed regulators of RGC differentiation (Atoh7, Brn3b, and Islet1), while a smaller subset co-expressed Brn3b and the mature RGC marker Thy1, thus confirming a RGC identity.

Scientists from the Sundrud lab have identified a normally small subset of immune cells that may play a major role in the development of Crohn's disease as well as steroid resistance associated with the disease.

Researchers have discovered that a subset of human antibodies have catalytic activity against a particular antigen, breaking it down into smaller and less harmful fragments instead of trapping it for removal or destruction by other immune cells.

Total 4E - BP1 and p - 4E - BP1 was predominantly cytoplasmic, although additional nuclear localization was seen in a small subset of tumor cells.

In small cell lung cancer, starting from bioinformatics analyses of large gene expression datasets, we clustered subsets of co-expressed gene modules, derived networks of transcription factors and simulated their dynamics using logic - based mathematical modeling.

A Small Case Series of Intravascular Large B - Cell Lymphoma with Unexpected Findings: Subset of Cases with Concomitant Extravascular Central Nervous System (CNS) Involvement Mimicking Primary...

Currently, stem cell therapies are known to be effective for only a small subset of diseases, mostly diseases that involve the blood - forming system.

These include: a) Global Clusters that consist of a small, tight subset of genes that are co-expressed under the entire spectrum of experimental conditions; b) Time Series of gene expression profiles during successive days of standard ES cell differentiation; c) Specific Gene Classes based on hierarchical clustering of transcriptional factors and ESTs; d) Expression Waves of genes with characteristic expression profiles during ES cell differentiation, juxtaposed to waves of genes that behave in the exact opposite way; e) Pathway Animations that illustrate dynamic changes in the components of individual KEGG signaling and metabolic pathways viewed in time - related manner; and, f) Search Engines to display the expression pattern of any transcript, or groups of transcripts, during the course of ES cell differentiation, or to query the association of candidate genes with various FunGenES database clusters.