Sentences with phrase «small tumors in»

This can make it hard to see small tumors in or around the dense tissue.

The researchers isolated tumor cells from patients and grew them to reproduce small tumors in the lab dish.

Not exact matches

The Company focuses on discovering and developing small molecule drugs directed against tumor and immune cell targets that control key metabolic pathways in the tumor microenvironment.

The targeted radiotherapy shrank tumors for 71 % of patients who had already failed standard chemotherapy, but these results came from a small trial that started with 30 patients and then added another 20 after positive data started rolling in.

It is a small tumor on my pituitary gland in my brain.

The study indicated that even a small period of breastfeeding reduces the risk of these stubborn tumors, which are more common in younger women and generally have a poorer prognosis than other subtypes of breast cancer.

Given the results of a a new study reported in the British medical journal, The Lancet4 that children and young adults scanned multiple times by CT have a small increased risk of leukemia and brain tumors in the decade following their first scan, parents should make sure a CT scan is really necessary in treatment of their child after head injury.

Residual tumors, spawned from the remaining cancer cells, were 3.5 times smaller in the treated mice than in untreated mice.

However, researchers have long thought that tumors don't release intact cells into the bloodstream until relatively late in the disease, and then only in vanishingly small numbers.

Even before treatment, cancer patients in the study had a small number of infection - and tumor - fighting T cells that target these unusual proteins, the researchers found.

According to the study, in the treatment of small renal tumors, the ideal outcome of both complete oncologic control and preservation of renal function is not presently available.

«Particularly in such patients with underlying CKD, our modeling results support the integration of renal tumor anatomic features at cross-sectional imaging into decision making for treatment of small renal masses and may be used to provide a patient - centered framework for selection of optimal candidates for ablative therapy,» Kang said.

Led by Stella K. Kang, a radiologist with the Department of Radiology at the New York School of Medicine, the study was designed to compare the effectiveness of a treatment algorithm for small renal tumors incorporating the nephrometry score, a renal tumor anatomy scoring system developed by urologists, with the current standard of uniformly recommended partial nephrectomy in patients with mild - to - moderate chronic kidney disease (CKD).

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

SURVIVAL GEAR Some genetic variants may have allowed a small number of Tasmanian devils to withstand a deadly contagious facial tumor that has killed up to 95 percent of them in some locales.

«Study in early stage breast cancer shows that even small tumors can be aggressive.»

Still, how melanoma cells join into tumors — whether by individual cells coming together or small or large clusters of cells doing so — follows the same pattern as breast tissue cancer cells: Cables are extended to reel in other cells or clusters.

When injected with cancer cells, animals housed there developed tumors 80 % smaller than those in control mice, or no tumors at all.

In some horses, tumors develop as small bumps under the skin or as scaly lesions that easily can be removed by a veterinarian, but in other horses the problem becomes much more seriouIn some horses, tumors develop as small bumps under the skin or as scaly lesions that easily can be removed by a veterinarian, but in other horses the problem becomes much more seriouin other horses the problem becomes much more serious.

The surgeons make a small incision in the patient's ear canal and use the endoscope to help find and remove the tumor.

Now researchers have taken a small step in that direction: They've deciphered a genetic «signature» that, in several tumor samples, appears to predict whether a cancer will spread.

In the last few years, a bulk of data pointing to a small population of cells in tumors that maintain tumor growth, are particularly resistant to chemotherapy, are responsible for relapses, and develop metastaseIn the last few years, a bulk of data pointing to a small population of cells in tumors that maintain tumor growth, are particularly resistant to chemotherapy, are responsible for relapses, and develop metastasein tumors that maintain tumor growth, are particularly resistant to chemotherapy, are responsible for relapses, and develop metastases.

Then Hamede Ross saw something even more remarkable: In five devils, the tumors got smaller and went away.

And a small number of glioblastoma patients do not have CMV in their tumors.

COLD SPRING HARBOR, N.Y. — When breast cancer spreads, it moves in gangs of ready - to - rumble tumor cells, a small genetic study suggests.

In contrast, the LDL - DHA rats had smaller, pale tumors with poor blood supply.

A global analysis of metabolites and small molecules in urine samples from patients with adrenal cancer has identified four biochemicals that, when measured together, can distinguish malignant from benign adrenal tumors, according to study results presented at the 2015 Annual Clinical Congress of the American College of Surgeons.

«Hodgkin lymphoma is unusual among cancers in that it consists of a small number of tumor cells in a sea of inflammatory cells and immune system cells, including T cells that don't work very effectively.»

«We wanted to utilize platelets» intrinsic tendencies to accumulate at wounds and to interact with circulating tumor cells, for targeted delivery of immune checkpoint inhibitors» said Gu, «Interestingly, we found the antibody can be promoted to release from activated platelets in the surgical site, due to generation of small platelet - derived microparticles upon the platelet activation.

According to Semenza, «Chemotherapy may kill more than 99 percent of the cancer cells in a tumor but fail to kill a small population of cancer stem cells that are responsible for subsequent cancer relapse and metastasis.»

The new «tumor in a dish» method begins by taking the cancerous tissue removed during surgery or biopsy, cutting it up into small pieces and putting them in a special collagen gel that maintains them as «organoids» that retain the three - dimensional structure of the original tumor and include supporting cells from the tumor's environment.

The approach was most successful in making a difference in samples from the two patients in which the smaller - sized tumor DNA was not readily apparent, which may represent patients with low tumor burden and previously difficult to detect circulating tumor DNA.

In a model of glioblastoma, a brain cancer that does not metastasize outside of the brain, they could readily see that the length of circulating tumor DNA was smaller than healthy DNA by 20 - 50 base pairs.

An advantage of small - molecule PPF — which has been previously used in clinical trials in an attempt to treat Alzheimer's disease and dementia — is that it can penetrate the blood - brain barrier and reach the tumor.

But in at least one case, a small tumor merged with the cells lining the faux blood vessel.

1 in 5: And even though you're a lot less likely to die of breast cancer these days, a New England Journal of Medicine article contends that we're pulling the trigger too early on treatment: For every one case of a small tumor caught early that would have been a health threat, about five essentially harmless tumors also receive the same treatment.

In patients likely to have surgery, close, active monitoring of small renal tumors confined to the kidneys is associated with low rates of tumor growth or death, according to a study by a researcher at the Icahn School of Medicine at Mount Sinai published in the September issue of The Journal of UrologIn patients likely to have surgery, close, active monitoring of small renal tumors confined to the kidneys is associated with low rates of tumor growth or death, according to a study by a researcher at the Icahn School of Medicine at Mount Sinai published in the September issue of The Journal of Urologin the September issue of The Journal of Urology.

He was part of a team that recognized that only about 10 % of patients with NSCLC responded to the small molecule erlotinib — those whose tumors harbored mutations in the gene encoding EGFR.

Results showed that tumor cells containing the protein carried anywhere from 10 to 17 times fewer breast stem cells, and tumors grown from the injected cells were about three times smaller than those in mice who had received tumor cells with depleted levels of HOXA5.

They found that, by using math models to understand the complex dynamics within cancers, they could use small changes in the environment to promote the growth of cells that are less aggressive and thereby decrease tumor growth.

In fact, the mice that received the complete nanomedicine package had smaller tumors and longer lifespans than their counterparts injected with saline, nanoparticles without the drug, the drug alone, and nanoparticles with the drug but without the targeting aptamers.

The researchers used computer models to predict that small changes of the pH within the tumor could tip the balance, decreasing the survival advantage of the invasive cells in favor of the non-invasive cells.

Now, MIT engineers have developed a far more sensitive way to reveal ovarian tumors: In tests in mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diameteIn tests in mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diametein mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diametein diameter.

In humans, colon cancer often spreads to the liver and forms small tumors that are difficult to detect, similar to ovarian tumors.

This model showed that in order to detect tumors 5 millimeters in diameter or smaller in humans, the researchers would need to improve the system's sensitivity by at least one order of magnitude.

The proportion of failed breast conservation surgery in these hospitals ranged from 3 - 32 %, while the proportion of mastectomies for small tumors ranged from 0 - 60 %.

By combining these two refinements, the researchers were able to enhance the sensitivity of the sensor 15-fold, which they showed was enough to detect ovarian cancer composed of small tumors (2 millimeters in diameter) in mice.

Among lung cancer patients; suicide SMR was higher in males (SMR = 8.8), Asians (SMR = 13.7), widowed patients (SMR = 11.6), older patients (70 - 75 years; SMR = 12), patients with undifferentiated tumors (SMR 8.6) or small cell lung carcinoma (SCLC) histology (SMR = 11.2), patients presenting with metastatic disease (SMR = 13.9) and in patients who refused to receive surgical treatment (SMR = 13).

Dr Jeremy Thomas, a consultant pathologist at the Western General Hospital, Edinburgh, UK, told the European Breast Cancer Conference that although the majority of women with DCIS received the correct surgery for their disease, large numbers of women were undergoing mastectomy for DCIS either as a result of failed breast conservation surgery or for tumors that turned out to be smaller than 20 mm in diameter and therefore should normally have had a lumpectomy rather than a mastectomy.

The total number of women who had mastectomies, including those for whom mastectomy was the first course of action as well as those who had failed breast conservation, was 2,479; of these, 510 (21 %) had mastectomies for tumors smaller than 20 mm in diameter, which would normally have been better treated with a lumpectomy.