Not exact matches
The company's therapeutic candidates are highly selective
sodium ion channel 1.7 (Naᵥ1.7) inhibitors based on naturally occurring
small molecules.
This
small protein molecule contains a loop which fits, like a key in a lock, into the
ion channel proteins found on nerve cell membranes, which are used to transport
sodium and potassium
ions in and out of the cell.
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Sodium ions are much
smaller than the hydrogen protons bound to oxygen molecules in the water in our bodies which are mapped by conventional MRI.
Sodium ions naturally occurring in the body are much
smaller than water molecules and are involved in many body functions associated with pathology.