Sentences with phrase «smaller than a mouse»

«Finding a galaxy as tiny as Segue 2 is like discovering an elephant smaller than a mouse,» said UC Irvine cosmologist James Bullock, co-author of the paper.

Not exact matches

Residual tumors, spawned from the remaining cancer cells, were 3.5 times smaller in the treated mice than in untreated mice.

In the study, led by post-doctoral fellow Long N. Nguyen of Duke - NUS, researchers found that mice without the Mfsd2a transporter had brains a third smaller than those with the transporter, and exhibited memory and learning deficits and high levels of anxiety.

Scientists imaged more than 1,700 mouse brains (injected with a tracer virus) at resolutions less than a micrometer, or 50 times smaller than a human hair.

Today, lab mice live in shoebox - size cages hundreds of thousands of times smaller than their natural ranges, and rats can't forage or even stand upright.

These modified mice had significantly smaller testes and lower sperm counts than their normal counterparts — and when the group bred them with normal females, they found that the litter size was around half normal.

When injected with cancer cells, animals housed there developed tumors 80 % smaller than those in control mice, or no tumors at all.

Pregnant mice engineered to have higher levels of Zika virus had smaller fetuses (top) than normal dams (bottom).

But the males — despite having smaller testes and lower sperm counts than normal mice — were clearly fertile and produced offspring.

While feasting, the animals — just slightly bigger than mice — huddle together in a small group and appear to lick each other's faces.

That's why elephants have smaller sperm than mice.

Moreover, mice engineered to generate smaller than normal quantities of SIRT1 carried relatively little fat in their blood, indicating that their cells hung onto it.

Mouse brains are physically smaller and grow faster than human brains.

Zeroing in on this kinase was encouraging, Goga said, because other researchers have shown that genetic - knockout mice that lack the entire family of PIM kinases are slightly smaller than normal mice, but «basically fine,» indicating that a drug targeting just PIM1 may have manageable levels of toxicity in breast cancer patients.

In rodents, differences in life expectancy and morbidity during aging are particularly high: Despite close relationships with regard to genetic aspects, small rodents like mice or rats live no longer than two to three years, whereas mole - rats or chinchillas have an average life span of 20 to 30 years while staying comparatively healthy.

Results showed that tumor cells containing the protein carried anywhere from 10 to 17 times fewer breast stem cells, and tumors grown from the injected cells were about three times smaller than those in mice who had received tumor cells with depleted levels of HOXA5.

In fact, the mice that received the complete nanomedicine package had smaller tumors and longer lifespans than their counterparts injected with saline, nanoparticles without the drug, the drug alone, and nanoparticles with the drug but without the targeting aptamers.

Mice, for example, have brains that are around a thousand times smaller than the human one.

Now, MIT engineers have developed a far more sensitive way to reveal ovarian tumors: In tests in mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diameter.

Their study showed that mice without the Y6 gene were smaller, and had less lean tissue, than normal mice.

To investigate, Akhtar deleted the gene for Rac1 in female mice; their first litter of pups survived, but they were smaller than normal — probably because the milk they received contained less fat and protein than normal.

Statistical analyses aimed at reconstructing how much an adult Archicebus would have weighed in life show that it was slightly smaller than the smallest living primates, which are pygmy mouse lemurs from Madagascar.

Further testing found these mice had lower - than - expected growth hormone and insulin - like growth factor (IGF1) levels in the blood, potentially explaining the small stature and delayed development seen in human patients.

The mouse genome is about 10 % smaller than the human genome, owing to a lower repetitive DNA content.

In experiments with lab mice, she discovered how small groups of cells dance about to form an embryo and how a layer of cells surrounding the embryo itself, previously thought of as nothing more than a protective cloak, orchestrates the formation of an embryo's body parts.

Female mice deprived of dietary zinc for a relatively short time before conception experienced fertility and pregnancy problems and had smaller, less - developed fetuses than mice that ingested zinc during the same times, according to researchers in Penn State's College of Agricultural Sciences.

The Mecp2 mutant mice were more sensitive to light touch; a small puff of air on their backs startled the rodents more than normal mice.

Fetuses from zinc - deficient mice in the study were 38 percent smaller on average than those from the control group fed a diet with zinc included.

Although these mice are smaller than their normally fed peers, they seem to retain their youthfulness and intellects well into their extended old age.

Stoke therapies that worked on small animals such as mice more often than not proved ineffective in human strokes.

The brains of the mice were smaller than normal and had fewer neurons in areas that controlled the affected behaviors.

One, called CISH, shuts down the receptor to a key growth hormone; mice that overproduce the receptor are smaller and grow more slowly than normal.

In mice, the skin lesions that were treated with the nanosponge - hydrogel were significantly smaller than those that were left untreated.

But mice lacking γ - actin, though typically smaller than normal and deaf, can survive to adulthood.

Although the slopes corresponding to adipocyte cross-sectional area for the subcutaneous depot were smaller than (and fell outside the 95 % confidence intervals of) the slopes for the mesenteric and perigonadal depots, this difference was entirely attributable to the fact that the data from three B6.V Lepob / ob mice fell below the line relating adipocyte area to macrophage content in the other animals (Table 1).

A mouse brain is a thousand times smaller than a human brain and lacks several kinds of brain cells that are abundant in humans.

Although CRISPR is incredibly useful for generating mutations by NHEJ and generating small mutations with HDR, when it comes to larger scale genome editing, such as replacement of a mouse gene with its human ortholog (greater than 5 kb), it remains to be seen whether CRISPR is as robust as conventional gene targeting.

Secondly, the mouse genome is significantly smaller than the human genome, making it possible to detect a large number of lineage - specific deletion events [17, 19].

In 12 mice, MRI was able to detect the one relatively large tumor, 17 out of 18 small tumors that were smaller than a millimeter, and 13 out of 16 milk ducts that were distended with carcinoma in situ, including some tumors less than 300 microns in width, about one - third of a millimeter.

The mouse genome is 14 percent smaller than the human genome and contains about 2.5 billion letters of DNA.

Note that I'm omitting a number of studies that show only small (less than 10 %) increases in maximum mouse life span, and also leaving out some work in progress that looks likely to enhance life span.

To better understand this complex tissues and its functions — and the diseases that affect it — a multicenter team led by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital has released a census of the cells that make up the lining of the small intestine, using gene expression profiles of more than 53,000 individual cells from the mouse gut or gut organoid models.

The tumors formed in mice co-treated with chidamide and decitabine were significantly smaller than those that formed in untreated animals or those treated with the single agents, starting from 15 days of treatment (Figure 4C, left panel), as visualized by 18F - fluorodeoxyglucose small - animal positron emission tomography — computed tomography at 21 days of treatment (Figure 4C, right panel).

Mice injected with a strain of the Zika virus lived longer and were measured to have smaller tumors than the control group, which was injected with saltwater.

Researchers comparing normal and obese mice found that obese mice produced more than twice as much of a small microRNA molecule called microRNA - 143 in their liversANCHOR.

Space for housing limited numbers of small animal species other than mice is also available upon request.

The differences between the two tg - mouse lines are smaller than the distinction from the controls.

Smaller, cheaper and easier to breed than mice, zebrafish in their juvenile phase can actually live in the tiny amount of liquid — ranging from tens of nanoliters to several milliliters — that fits in the wells of a standard 96 - well plate used to screen drug compounds.

CRISPR not only allows researchers to create these animals faster and more precisely than before, but also to move beyond a relatively small menagerie of standard model species — fruit flies, mice, zebrafish — to create a Noah's ark of mutant dogs, pigs, primates and more.

Protein powder can have an effect on pregnancy — A study on mice found that a high protein diet led to smaller birth weight than a low protein / high carbohydrate diet (24).