Sentences with phrase «smaller than the human genome»

The mouse genome is about 10 % smaller than the human genome, owing to a lower repetitive DNA content.

The bowhead whale genome is slightly smaller than the human genome and the typical mammalian genome.

Secondly, the mouse genome is significantly smaller than the human genome, making it possible to detect a large number of lineage - specific deletion events [17, 19].

The mouse genome is 14 percent smaller than the human genome and contains about 2.5 billion letters of DNA.

Not exact matches

«Because the primary Small Intestine Chip recapitulates the physical microenvironment that cells experience inside the human body, such as fluid flow and cyclic peristalsis - like stretching motions, it exhibits a genome - wide gene expression profile that comes closer to its in vivo counterpart than that of the same intestinal cells grown as 3D organoids,» said first - author Magdalena Kasendra, Ph.D., a former Postdoctoral Fellow on Ingber's team and now Principal Scientist at Emulate, Inc. in Boston.

Although CRISPR is incredibly useful for generating mutations by NHEJ and generating small mutations with HDR, when it comes to larger scale genome editing, such as replacement of a mouse gene with its human ortholog (greater than 5 kb), it remains to be seen whether CRISPR is as robust as conventional gene targeting.

By analyzing these two exomes together with the genome sequence of a Neandertal from Siberia we show that the genetic diversity of Neandertals was lower than that of present - day humans and that the pattern of coding variation suggests that Neandertal populations were small and isolated from one another.

They identified more than 33,000 protein - coding genes, placing the octopus genome at slightly smaller in size, but with more genes, than a human genome.

Next - generation sequencing involves the application of glass micro-chip based methods and small - volume liquid handling (microfluidics) to sequence DNA more quickly and more cheaply than ever before, indeed 1000s times less costly than the technology used to sequence the first human genome just a few years ago.

What was humbling was that, when the number of genes in human cells were counted and compared to other organisms, our genome was considerably smaller than that of many other species.