Endothelial cell activation, vascular
smooth muscle dysfunction, oxidative stress, and inflammation, mechanisms which underlie heart disease, diabetes, and hypertension, are all variables which can precipitate or perpetuate immune imbalances in autoimmune disease.
«One way of treating patients with limb - girdle muscular dystrophy might be to use a gene transfer approach to treat the muscular dystrophy, and a pharmacological approach to treat
the smooth muscle dysfunction,» he said.
Not exact matches
In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial / vascular
smooth muscle cell
dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.
Vascular endothelial
dysfunction promotes vasoconstriction and favors platelet aggregation, white blood cell adhesion, and
smooth muscle cell proliferation.