Not exact matches
The Berkeley researchers developed their own statistical methods
so that they could use data from virtually all of the temperature stations on land — some 39,000 in all — whereas the other
research groups relied on subsets of data from
several thousand sites to build their records.
In April, an investigation at Rutgers University finally concluded that «substantial (clear and convincing) evidence exists that
research fraud has occurred in
several areas» including «biased selection of subjects who were to be included in the symmetry / asymmetry comparison
groups so as to artificially obtain desired results.»
Particularly relevant have been the programs supporting scientists
so that they can spend time in other European laboratories, but also various collaborative projects encompassing
several research groups across many countries.
In 1996, in response to these concerns, Varmus, then director of NIH, impaneled a
group of experienced clinical investigators and academic health center administrators to make recommendations that might guide the NIH toward policy changes to alleviate the concerns in the clinical
research community.14 Several of the panel's recommendations have been implemented, including increased support of the General Clinical Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented r
research community.14
Several of the panel's recommendations have been implemented, including increased support of the General Clinical
Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented r
Research Center budget, expanded support of training in clinical
research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented r
research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review
groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented
researchresearch.
Stress resistance has not been assessed however and
so the biological relevance of this finding is currently unknown.32
Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER
group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER
group and increase in the CER
group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both
groups after three months.48 Summary and Future
Research Directions
As with many initiatives there are
several organizations — each with their own focus —
so it's up to interested dog owners to do their
research and reach out to fellow dog owners before deciding which
group to join.