Sentences with phrase «so unfavorable»

Stocking an independent title means taking on a degree of risk that most booksellers aren't willing to accept, so these unfavorable terms have long been a barrier to getting indie books on shelves.

At no other time in memory have both major party candidates been so unfavorable.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

The Republican presidential frontrunner said his attendance in recent years resulted in various unfavorable reports regarding his perceived inability to take a joke, so Trump will skip the dinner later this month, to be hosted by The Nightly Show host Larry Wilmore, despite receiving numerous invitations from media groups.

As of last week, the Market Climate for stocks was characterized by unusually unfavorable valuations, and market action so tenuous that it is indistinguishable from unfavorable action.

So again, the net effect of Wednesday's rally is to perpetuate an unfavorable Market Climate.

In short, we are open to «softening» our hedge somewhat in the event that market action exhibits sufficient improvement in price / volume behavior, breadth, industry action, and so forth, but here and now we continue to identify the Market Climate as unfavorable.

We know the society in Syria Iraq or Afghanistan is likely to treat us as westerners unfavorable so we do nt go there and risk having our heads cut off.

But she believed that God provided opportunities for the faithful, even in the most unfavorable circumstances: «When so rich a harvest is before us why do we not gather it?

So after eating what was edible and tossing the rest (how do you do that btw, I always feel so bad throwing away the unfavorable outcomes...) I tweaked it as follows, went back today and now it's greaSo after eating what was edible and tossing the rest (how do you do that btw, I always feel so bad throwing away the unfavorable outcomes...) I tweaked it as follows, went back today and now it's greaso bad throwing away the unfavorable outcomes...) I tweaked it as follows, went back today and now it's great!

I do research on insect pest and disease resistance and drought tolerance to develop rice plants that are sturdy under unfavorable conditions so that their grain yield is not drastically reduced.

While old QSR chains are trying to save their consumer base, shed unfavorable brand identities and catch up, UFood Grill is already in a leadership position to expand what we already do so well.»

If so, it's stupid to sit there and bitch and moan about the Rays being cheap when they are just in an unfavorable situation.

So Wax and his colleagues were heroes when they published data favorable to homebirth, but now part of «conspiracy» to defame homebirth when they publish data that is unfavorable to homebirth.

The problem for him is not so much the overall number, but the unfavorable rating.

At hisfundraiser Thursday night, he told the 600 - or - so guests that «there are billionaire media owners who don't want to see change in this city,» alleging that unfavorable coverage of his administration is the result of a biased media.

«However, doing so is resource - intensive and comes at considerable risk for individual journals in the form of unfavorable evidence and bad press.»

One of the many reasons tumors are so difficult to treat is that they are able to adapt whenever they are exposed to unfavorable conditions.

First of all, the anatomy of your shoulders is determined by genetics, so guys with more favorable shoulder genetics will reap better results faster than guys who have, for example, narrower shoulders, unfavorable limb length and «worse» muscle attachments (which define how efficient the muscles are, biomechanically speaking).

Why are so many women suffering from unfavorable symptoms even through their doctors say their blood work is fine?

It isn't so much the presence of animal protein and fat that gives rise to unfavorable bacteria, it's the absence of plant fiber.

So am I being a hypocrite if I put fragrance in the «Unfavorable ingredients» category?

A beautiful but stolid, screamingly boring period piece with acting so wooden as to invite unfavorable comparison to a collection of popsicle sticks.

Unions in states with unfavorable labor law that are able to function without agency fees do so partly because they have support from the states that do have agency fees.

But I want to encourage those writers to keep indie publishing in the back of their mind so that if they find themselves in the position of a contract that has unfavorable terms or working with an editor who wants changes that will not be true to the spirit and intended vision of the book, they don't just TAKE IT because they have to.

Of course, it would not be ethical to pay them to write an entirely positive review, so be ready to read some unfavorable remarks.

We conclude that withdrawing 4 % (plus inflation) is doable just so long as we can avoid being hurt by an unfavorable speculative return.

Even if you need cash fast, it's crucial to take a few minutes to look at your options so you don't get locked into an unfavorable deal.

Royal Canin Urinary SO Index ® promotes a urinary environment unfavorable to the development of both struvite and calcium oxalate crystals

In the event that we do cross an open passage or expect unfavorable weather, the captain will give notice so that guests can prepare accordingly.

But there's a catch: Points often transfer at an unfavorable exchange rate, so it may not be the best value per point.

Post-publication review, critique, favorable or unfavorable citation, and so on, are really the heart of the scientific peer - review process, once review for publication gets a report into this process.

So in other words, for contrarians the environment appears to have become very unfavorable for development.

For example, almost the entire north atlantic has been unfavorable for TC development the last week, but the SSTs are still so high that one of the only areas where a hurricance could conceivably form just formed one.

«The reality is that the temperature and other data has become unfavorable to their climate theory, so they hide behind complexity and authority instead of simply telling you what is going on.»

Harassment occurs when remarks are so frequent and / or severe that it creates an offensive or hostile work environment, or the behavior results in an unfavorable employment decision.

Our mid-size firms are vulnerable to being taken over due to the lack of protection in our securities and foreign investment laws, unfavorable currency exchange rates, and the so - called Canadian discount, which depresses the trading value (and therefore trading volume) of our stock by 20 per cent or so.

«Unfortunately, juries typically have an unfavorable view of motorcyclists, so we often consider that bias when we prepare a case pursuing damages in a personal injury lawsuit involving a motorcycle.

A spokesperson for the company on Thursday said that Uber is waiting for the court's final decision, adding that Uber will continue operating in most European countries like it did so far even if it's hit with an unfavorable verdict and noting that the case is primarily significant due to the fact that it could prompt many European countries to change their outdated transportation laws.

So ask yourself if you were really «on a sabbatical» as your resume says, or are you using that term to cover up unfavorable aspects of your work history?

CBT helps you to become aware of adverse or untrue thinking patterns so you can change your thinking and view challenging, triggering or unfavorable situations more clearly and react in a more positive way.

In general, home studies are pretty thorough and check out the potential parents with so many checks and balances that any unfavorable information would come out.

Also FYI, make sure you read into the description of the NACA loan, because from what I remember, they have some really unfavorable criteria for investors, so just double check before you use it.