The adult age - related clinical syndrome of growth hormone deficiency includes
increased fat mass, decreased muscle mass and strength, decreased bone
density, elevated lipids, insulin resistance, decreased psychosocial well - being and depression, fatigue,
increased social isolation, inability to handle stress, cardiovascular disease, memory decline, overall deterioration in quality of life, frailty, thin dry skin,
increased wrinkles, and diminished exercise tolerance.
In the United States for instance,
social anthropologists have noted that body size, body height, muscle mass, and bone
density all
increased in a dramatic and very advantageous way when Americans began to introduce more protein and calcium - containing foods into the diet in the latter part of the industrial era.
Class
density and size
Increases in class
density or overcrowding have been associated with behavioural problems, aggression,
social withdrawal, dissatisfaction and stress, resulting in less time spent in group involvement and more time in solitary play.