Sentences with phrase «sodium excretion also»
In the CKD study, BMI and sex were the primary cardiovascular risk variables but sodium excretion also contributed to cardiovascular risk of hypertensives.
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«Further, the study also showed that consuming larger amounts of potassium in the diet counterbalances the adverse affect of high sodium excretion on blood pressure in cardiovascular disease outcomes.»
While age also affects cardiovascular risk, age was similar across sodium excretion categories and hence not a significant factor.
The study also found that those with hypertension, but not those without hypertension, are at increased risk when sodium excretion exceeds 7 grams per day.
-RCB- elevated sodium level within kidneys, either as a result of pathological bottleneck such as reduced number of nephrons, or simply due to heightened intake - or both - may activate pro-inflammatory cytokines and chemokines in proximal tubular cells, may cause oxidative stress by activating ROS - producing NADH oxidase enzymes, or blood vessel constriction by inhibiting kidney arginine transport and nitric oxide synthesis; elevated renal inflammation, oxidative stress and restricted blood flow all can impair the efficacy of sodium excretion, more so combined (if extensive, it can also result in post-natal reduction of nephron units)