Sentences with phrase «sofosbuvir not»

In tests using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate neurons and other brain cell types — the scientists found that exposure to sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.

Not exact matches

«Given the absence to date of alternative therapies for patients with genotype 2 or 3 who have failed interferon therapy or for whom it is not an option, treatment with the new sofosbuvir regimen offers a vast improvement,» Dr. Jacobson says.

The U.S. Food and Drug Administration (FDA) has not yet approved sofosbuvir.

A study presented today that evaluated an investigational dosage of once - daily ledipasvir 45 mg / sofosbuvir 200 mg (LDV / SOF) in children aged six to 11 years infected with the Hepatitis C virus (HCV), found that 99 % of children (n = 89/90) had undetectable levels of HCV - RNA 12 weeks after treatment.

In a more advanced trial, 12 weeks of sofosbuvir plus ribavirin yielded the same results as 24 weeks of interferon plus ribavirin: 67 percent of patients had no evidence of the virus in their blood (although side effects such as fever and depression were fewer among patients who did not receive interferon).

Moreover, fetuses of Zika - infected pregnant mice did not show detectable Zika virus amplification in the sofosbuvir - treated group.