Currently, there are several existing FDA - approved blocking drugs for this protein including rapamycin, currently used primarily as an immunosuppressant
after solid organ transplantation.
Research led by a University of Cincinnati (UC) scientist shows the impact of acute kidney injury requiring dialysis (AKI - D) on patients receiving
non-renal solid organ transplantation (NRSOT), including cardiac and liver transplantation.
As a result, they are currently being investigated as a cellular therapeutic for the treatment of autoimmune diseases and long - term patient and graft survival
following solid organ transplantation, and allogeneic hematopoietic stem cell transplantation.
It is to be noted that all research other than Trivedi et al, has been carried out on BM derived MSC and all trials have been performed
after solid organ transplantation.
«Furthermore, this strategy may be beneficial for other pathological settings in which elevated numbers of regulatory T cells are desirable, such as autoimmune diseases and
solid organ transplantation,» Beilhack says.
The Unit aims at studying and modulating antigen (Ag)- specific immune responses, to develop efficient therapeutic approaches to (re) establish Ag - specific immune tolerance in allogeneic bone marrow and
solid organ transplantation, autoimmune diseases, allergy, and gene therapy.
Such work is accelerating therapeutic advances in autoimmunity,
solid organ transplantation, and cancer immunotherapy.
As inaugural director of the Transplantation Institute, Fung will work with faculty from multiple academic departments to grow UChicago Medicine's programs in
solid organ transplantation.
Principals of Nursing Practice - General Med / Surg Unit Post-operative care for adults having
solid organ transplantation and bariatric surgery.