BCR / TCR Genic / Regional Probes (372): recognizing transcripts from genes that undergo
somatic rearrangement.
Details on the recurrently mutated genes, and structural and functional analysis of
somatic rearrangements, are provided as supplementary materials.
Not exact matches
Dr. Vasmatzis» research on the «Quantification of
Somatic Chromosomal
Rearrangements in Circulating Cell - free DNA From Ovarian Cancers» is published in the July 20 edition of Scientific Reports.
In fact,
somatic ETV6 translocation is the most common gene
rearrangement in childhood leukemia.
On average, the authors 1,140
somatic mutations, including 154 that altered protein sequence, and 12
somatic structural
rearrangements.
Our NGS kits are used to detect clonal gene
rearrangements,
somatic hypermutations and for the study of MRD.
Extensive PCR - based validation yielded almost 23,000
somatic substitutions and over a hundred structural events (indels and
rearrangements).
A number of Invivoscribe LymphoTrack Assays, formatted for use on both the Illumina MiSeq ® and Thermo Fisher Ion PGM ™ platforms, were designed to detect
somatic gene
rearrangements within the antigen receptor loci.