However welcome the recent announcement that a team of scientists based at Newcastle University, has grown a section of human liver using stem cells from umbilical cords, rather than from the more controversial
source of embryonic stem cells, and whatever the eventual promise or potential of harvesting organs for transplantation from genetically modified pigs, the benefits of either of these two pioneering techniques to currently dying / suffering patients, remain both elusive and distant.
Attempts have been made to bridge this divide by proposing alternative
sources of embryonic stem cells for research and therapeutic purposes.
Not exact matches
According to the National Institutes
of Health's definition, however, pluripotent
embryonic stem cells are «the
embryonic source of all
cells of the body.»
The NIH defines totipotent
cells as the
source of both
embryonic stem cells and
of trophoblast
cells which give rise to extra-
embryonic tissues such as the placenta.
But on the same day, he also revoked the very kind
of policy that promoted the «purple» governance he claimed to want, e.g., Bush's directive that funding priority be given to funding non
embryonic — and hence, societally uniting
sources of pluripotent
stem cells — even though they had already been discovered in the induced pluripotent
stem cell breakthrough.
It made the front page
of the New York Times, but don't let that dissuade you ¯ reports today about new ethical
sources of embryonic - type
stem cells are credible, and they are very good news.
Not that a principled moral objection shouldn't be enough, but, for those sitting on the fence, the additional discoveries
of alternative
sources of embryonic - type
stem cells should be decisive.
Stem cells from breast milk can grow into many other kinds of human tissue, raising hopes of an ethical source of embryonic - like stem c
Stem cells from breast milk can grow into many other kinds
of human tissue, raising hopes
of an ethical
source of embryonic - like
stem c
stem cells
«We can work with any
embryonic stem cell line from any
source and are not restricted to working with the very small number
of federally approved lines as is the case for researchers in the United States,» says Minger.
But
embryonic clones, the
source of an endless supply
of stem cells imprinted with one's personal DNA, could alter the equation in favor
of the patient and augur a paradigm shift in medicine on par with the changes brought about by antibiotics and vaccines.
Scientists have created red blood
cells from human
embryonic stem cells, in a step that they say could mean an infinite
source of blood for transfusions.
After hearing a brief explanation that laid out the different
sources of stem cells (but left undiscussed their current uses or future potential for therapy), the respondents offered a slightly more nuanced set
of views, and only a slight majority (52 %) supported
embryonic stem cell research.
Derivation
of pluripotent
stem cells, either
of embryonic origin or following genetic reprogramming, has opened the path for an alternative
source for epidermal
cell therapy as these
cells are both immortal and pluripotent, theoretically capable
of providing any requested number
of cells of any desired phenotype.
Human
Embryonic Stem (hES)
cells derived from Preimplantation Genetic Diagnosed (PGD)- embryos offer a new alternative
source of cellular model as they can be largely expanded, differentiated in several
cell types and harbors «naturally» the causative mutation
of the pathology.
For the first time, through the use
of human
embryonic stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
stem cells (hES)
sourced from pre-implantation diagnosis, researchers from Inserm's Institute for
Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem Cell Therapy and Exploration
of Monogenic Diseases (I -
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystrophy.
Embryonic stem cells (ESCs) represent a
source for the large numbers
of modified EPCs required to therapeutically inhibit tumorigenesis [3], although patient - specific induced pluripotent
stem cells (iPSCs) represent a more attractive option.
The aorta - gonad - mesonephros (AGM) region in the aortic wall appears to be the most important
source of new blood
cells, and it has been found to contain numerous hematopoietic
stem cells by day 11
of mouse
embryonic development.
LifeMap Discovery ® is a compendium
of embryonic development for
stem cell research and regenerative medicine, constructed by integrating extensive molecular, cellular, anatomical and medical data curated from scientific literature and high - throughput data
sources.
We are the home
of the UK
Stem Cell Bank which provides a world - leading resource of ethically - sourced, quality - controlled human embryonic and other stem cell lines for research applicati
Stem Cell Bank which provides a world - leading resource of ethically - sourced, quality - controlled human embryonic and other stem cell lines for research applicati
Cell Bank which provides a world - leading resource
of ethically -
sourced, quality - controlled human
embryonic and other
stem cell lines for research applicati
stem cell lines for research applicati
cell lines for research applications.
The backgrounder below provides summary main points and
sources on the position
of current NIH Director Dr. Francis Collins in support
of human
embryonic stem cell research, human cloning, and the creation
of ethically - questionable human - animal chimeras.
But, by then, human
embryonic stem cells had lost some
of their controversial edge, because scientists really had developed an alternative
source of cells that reduced the need for material from human embryos.
«This discovery will advance our understanding
of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties
of ES
cells, and help researchers with the rich
source of information to better understand some
of the unique features — such as self - renewal and pluripotency —
of human
embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member
of the Singapore team that conducted this research.
Until then, however, «although there is excitement that iPS
cells can serve as an embryo - free
source of stem cells,» says Lanza, «it would be premature to abandon research using
embryonic stem cells until we fully understand what's causing these problems.»
The excitement surrounding cellular reprogramming and the possibility
of federal funding for human
embryonic stem cell (ESC) research in the US could be overshadowing another promising therapeutic
source of stem cells: those derived via parthenogenesis, some researchers say.
The discovery, by scientists at Kyoto University and the University
of Wisconsin - Madison, seemed to promise a way out
of the bitter debates over
embryonic -
stem -
cell research: rather than using human embryos as a
source of stem cells, produce them from adult
cells.
In September 2010, The New York Times reported that the U.S. Court
of Appeals ruled that federal funding
of embryonic stem cell research could continue under the new rules while the court considers Judge Lamberth's ruling [
source: New York Times].
Alternatively,
embryonic stem (ES)
cells have emerged as a potential
source of less immunogenic hematopoietic progenitor
cells (HPCs).
Using cloning technology to derive
embryonic stem cells genetically identical to a patient is potentially very important, not only to provide a
source of cells that may be used to cure patients, but also to allow for genetic disease to be studied and potential drug treatments to be explored in the laboratory.
Human
embryonic stem cells (hESCs) could serve as an expandable
source for neurons production, which could be applied for the treatment
of various diseases affecting brain.