Not exact matches
«My lab works on the neural bases of
learning and memory,» says Pozzo - Miller, «so we decided to test if LM22A - 4 was able to improve
spatial discrimination
deficits by enhancing synaptic plasticity in the hippocampus, the brain region responsible for
spatial learning and memory.»
There was no difference between mutant and normal mice when it came to investigating an empty cage, however, and the mutants even outperformed normal mice on a test of
spatial learning and memory, suggesting that their
deficit was specific for social behavior.
First, the Morris maze can detect similar
deficits in
spatial learning and memory across species.
A
deficit in procedural
learning can alter performance in the hidden - target task and confound the interpretation of
spatial memory.
Analysis of the distance, latency, and cumulative search error (CSE) rank - summary scores revealed that MCI - AD patients and hAPP mice were significantly impaired in this task (Table 1 and Figure 1, B — D and F — I), consistent with a
deficit in hippocampus - dependent
spatial learning.
http://onlinelibrary.wiley.com/doi/10.1002/asia.201600259/full Subcutaneous administration of cyclodextrin significantly improved
spatial learning and memory
deficits in Alzheimer disease mice model doi: 10.1084 / jem.20121239.