Sentences with phrase «specific rna»

Successful FDA - supervised trials So far successful trials on 100 hives in Florida from March to June demonstrated that feeding IAPV specific RNA prior to virus inoculation dramatically improved bee - to - brood ratio and honey yield compared with bees inoculated with IAPV only.

Messenger RNA (mRNA) is the specific RNA sequence which is translated into an amino acid sequence that makes up a protein.

When human immune system proteins detect this virus - specific RNA, they sound an alarm to signal the rest of the immune system to respond.

An AU - rich element in the 3 ′ untranslated region of the spinach chloroplast petD gene participates in sequence - specific RNA - protein complex formation

The team investigated the proteome of Salmonella Typhimurium mutant strains lacking specific RNA - binding proteins that mediate the translation of RNA into protein (post-transcriptional control) and the parent strain.

Methods: The researchers used capillary liquid chromatography - mass spectrometry analyses to analyze the proteomes of Salmonella mutant strains lacking specific RNA - binding proteins that mediate the translation of RNA into protein (post-transcriptional control) and the parent strain grown under four different conditions.

IFN - gamma induces assembly of the 4 - protein, IFN - Gamma - Activated Inhibitor of Translation (GAIT) complex, that binds a specific RNA element in the 3» untranslated region of target mRNAs, and inhibits translation.

For nearly a decade, Sattler made contributions to RNA research, working to tease out how RNA binding proteins uniquely bind to specific RNA and regulate gene expression.

These questions led Darnell's lab to discover and explore the function of neuron - specific RNA - binding proteins in the mammalian brain.

smFISH can be used to detect specific RNA sequences in a cell based on their binding to a fluorescent probe, but imaging the «dots» corresponding to each RNA molecule requires high magnification and delicate imaging settings.

Determinants of specific RNA interference - mediated silencing of human β - globin alleles differing by a single nucleotide polymorphism.

Specific RNA binding to ordered phospholipid bilayers.

In a study featured in the journal Science, Dr. Feng Zhang and his colleagues at the Broad Institute at MIT described how they were able to engineer the C2c2 enzyme in order to search out and break apart specific RNA chemical sequences.

-- We can now use sequencing chemistry directly in cancer tissue speciemens to read the genetic code and obtain information of specific RNA molecules in individual cells in their original context in the tissue.

RNA interference, or gene silencing, is a way to destroy specific RNA messages so that a particular protein is not made.

Transgenic plants that express insect - specific RNA in chloroplasts kill pests through RNA interference [Also see Report by Zhang et al..]

The signal, which has been known for a long time, involves an enzyme present in every cell of the body, called PKR, which remains silent unless it is activated by a specific RNA structure thought to occur only in RNA made by viruses.

The study, published by the journal Proceedings of the National Academy of Sciences, demonstrates that the Disney lab's compound, known as Targaprimir - 96, triggers breast cancer cells to kill themselves via programmed cell death by precisely targeting a specific RNA that ignites the cancer.

Qβ takes over the host cell's protein machine to synthesise its envelope proteins, as well as a virus - specific RNA polymerase, called a replicase.

Kiebler and his group had previously shown that the brain - specific RNA - binding protein Staufen2 (Stau2) plays a central role in the transport of mRNAs from the cell nucleus to synaptic ribosomes.

In this webinar, Mr. Weldon will cover the architecture and technology background for SmartFlare RNA detection probes, which enable the detection of specific RNA's within live cells.

Expression of these genes appears in the blood in the form of specific RNA transcripts.

Liang said that specific RNA editing processes, adenosine - to - inosine (A-to-I), are plentiful in the human genome but have not been investigated in depth.

Together, these signals activate ADAR1, which edits specific RNA in a way that stabilizes a gene that can make cancer stem cells more aggressive.

Antisense drugs are essentially pieces of DNA that bind to specific RNAs — the recipe that cells use to make proteins.

We found that specific RNAs are only read at precise stages in order to produce the right protein needed to steer the axon at the right time.

Not exact matches

In the human version, scientists use an RNA guide to direct an enzyme, Cas - 9, to a specific point in any organism's DNA — where, like an eagle - eyed copy editor, the enzyme snips out an errant letter or sequence as if it were expunging a typo.

Says Roberts: «He quickly figured out that if Illumina was successful, it would need more than the world's supply of oligonucleotides» — the short snippets of nucleic acid that are designed to pair up with specific genetic sequences, and which are critical for DNA or RNA analysis.

Only in the past decade has RNA been discovered to carry out a wide variety of specific tasks in genetics, such as turning particular genes on or off.

Molecular biology's famous «Central Dogma» states that DNA, the living computer code that makes up our genes, is first transcribed into RNA, which is then translated into specific proteins, which ultimately do the 24/7 work of the body and form its many structures.

The new research, published recently as two separate studies in ACS Central Science and the Journal of the American Chemical Society, demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.

Dr. Sharp and project co-leader Joshua Nosanchuk, M.D., professor of medicine at Einstein and attending physician, infectious diseases at Montefiore Medical Center, developed a wound - healing therapy that uses molecules of silencing RNA (siRNAs) specific for FL2.

Every tissue in an organism contains a variety of messenger RNA molecules, single - stranded nucleotide sequences bearing instructions for the making of specific proteins.

«You'll see a bimodal distribution, with Bachelor's graduates trained in specific fields such as RNA interference or signaling pathways and the Ph.D. s who can be project leaders and investigators.»

It is emerging that the chemical structure of RNA molecules is extensively modified by specific enzymes normally present in our cells, which are commonly found to be altered in severe medical syndromes and various types of cancers.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

The assay was found to be 100 % sensitive and 100 % specific to ZIKV RNA from semen samples with a limit of detection of 5 viral copies per mL of semen.

Ribozymes derived from the self - splicing pre-ribosomal RNA of Tetrahymena act as sequence - specific endonucleases.

Novartis currently employs over 1,200 people in Cambridge and plans to continue expanding albeit only in specific areas such as biologic drugs like monoclonal antibodies and RNA interference molecules.

To test the hypothesis, sperm RNA elements corresponding to specific genes were characterized as a function of disease association.

Zika, dengue and chikungunya (which are also found in Colombia) are RNA viruses, which refers to how they encode their genetic material, and each is transmitted by a specific mosquito called Aedes aegypti.

A rapid, specific, sensitive, and inexpensive method has been developed that detects RNA from a Zika virus strain associated with the current outbreak.

A short, guide RNA leads the DNA - cutting enzyme Cas9 to specific places in the genetic instructions that scientists want to slice.

It is based on the design of a small RNA (RNAsg) that is complementary and specific to a 20 nucleotide DNA region.

Sosa and I pulled on latex gloves and carefully pipetted liquids into tubes to make our guide RNA from scratch — we first synthesized DNA strands with a specific sequence we wanted, used that as a template for the RNA, then destroyed the DNA and isolated the guide RNA from our test tube mixture.

To minimize the chances of a vaccine - induced infection, the researchers changed one specific amino acid in the RNA polymerase (a phenylalanine) to another amino acid (a tryptophan).

However, I doubt that nature is so wasteful with resources that it would produce such masses of RNA for no specific reason.»

Scientists have begun designing their own short interfering RNA against specific viral targets.

«For example, we now know that RNA can be methylated just like DNA and in a highly specific way,» says Dr. Manel Esteller, «and even more recently we observed that these epigenetic modifications of RNA may be key in the regulation of «guardian» RNAs, also called non-coding RNAs.»

The findings also reveal an unexpected connection between an RNA processing mechanism and protective immunity in a specific region of the brain.