The CRISPR - Cas technology generates
specific animal models of disease and is transforming model generation in mice, rats, rabbits, and larger animals.
Not exact matches
The researchers» strategy — generating
disease -
specific nerve cells, identifying a causative gene for developmental defects, validating the gene -
specific defect in
animal models, and then investigating interactions with other genes both in
animal models and in humans — represents a promising new approach for understanding the mechanisms underlying some
of the most intractable psychiatric illnesses.
As one
of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic molecular biology
of aging, from assisting in the investigation
of how
specific drugs can extend lifespan in simple
model organisms such as the nematode C. elegans, to facilitating studies in various
animal models of age - related
disease.