Sentences with phrase «specific brain disease»

It is not an infection or a specific brain disease.

Not exact matches

In a description of a sleep disorder known as RBD, in which patients enact their dreams through movement, he notes that a deficiency of dopamine (a specific brain neurotransmitter) is one key marker of Parkinson's disease.

Hasker's third proposition is that for the problem of divine non-intervention to be a real problem, «we must be able to identify specific kinds of cases in which God morally ought to intervene but does not» Many critics of (traditional) theism probably already have a more or less vague list of such cases, which might include genocidal events, such as the Nazi holocaust and the Rwandan massacre; wars; large - scale natural disasters; conditions of chronic poverty, in which millions of children die from starvation or are permanently stunted because of inadequate protein; the sexual molestation of children, which often leaves them psychologically scarred for the rest of their lives; death preceded by long, painful illnesses, such as cancer or AIDS, or by mind - destroying conditions, such as Alzheimer's disease; and the kinds of events described by Dostoyevski, such as the soldier using his pistol to get a mother's baby to giggle with delight and then blowing its brains out.

Includes chapters highlighting functional food opportunities for specific health issues such as obesity, immunity, brain health, heart disease and the development of children.

Specific plans for the research will remain to be developed, but potential areas under discussion include accelerating the pace of discovery to support the most innovative and promising science of the brain, including: chronic traumatic encephalopathy (CTE); concussion management and treatment; and the understanding of the potential relationship between traumatic brain injury and late - life neurodegenerative disorders, especially Alzheimer's disease.

Gene therapy delivered to a specific part of the brain reverses symptoms of depression in a mouse model of the disease — potentially laying the groundwork for a new approach to treating severe cases of human depression in which drugs are ineffective.

«Now we have two interesting models that are selectively targeting specific parts of the brain: the thalamus in FFI and the hippocampus in CJD,» says Jackson, who is now a Group Leader at the German Center for Neurodegenerative Disease.

«Only by understanding the complexities of what happens in specific cell - types found in specific areas of the brain during this disease can targeted treatments for Parkinson's disease be produced.»

«Women have more active brains than men: Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer's Disease.»

It is expected to have implications for other tissue - specific nuclear membrane conditions, such as fat, skin, bone and brain diseases, cardiomyopathy and an ageing disease known as progeria.

A neurosurgical procedure in which an implanted neurostimulator delivers electrical signals to specific areas of the brain to help regulate abnormal signals, DBS is currently only approved in the U.S. for the treatment of Parkinson's disease and essential tremor.

Although research demonstrates deposition in brain tissues, no specific symptoms or diseases have been linked to this finding.

All of the diseases, which cause the death of brain cells involved in controlling body movements, have recently been traced to specific genes.

Myelin is the protective sheath that insulates nerve fibers in the brain, and it is the primary site of injury in MS.. What's more, the scientists were able to pinpoint a specific protein in the blood, the blood - clotting factor fibrinogen, as the trigger for the disease - causing process.

New protein biomarkers would ideally show specific brain pathologies and act as early indicators of disease.

The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.

The researchers hope their new cell lines will be a useful resource for studying the cellular and molecular intricacies of Huntington's further, and suggest they may provide a model for examining other diseases of the brain that are specific to humans.

Thus, based on the robust findings from the current study and until proven otherwise, WBRT may still have an important role for treatment of patients who are not in this specific disease category (i.e., 1 - 3 brain metastases).

For example, how genetic programs affect the function of specific cell types, how they vary early or later in life and how dysfunction in these programs might contribute to disease, all of which could help scientists learn more about the fundamental workings of the brain.

«The presence of amyloid and tau pathology in aged chimpanzees indicates these Alzheimer's disease lesions are not specific to the human brain as generally believed,» Hof continued.

The researchers studied the brains of people who died from HD and those who died of other, non-neurological diseases and identified a very specific genetic signal that strongly correlates disease severity and extent of neuronal, or brain cell death.

The results suggest that, theoretically, delivering targeted, selective, and specific brain stimulation might improve some of the cognitive aspects of losing dopamine in Parkinson's disease.»

Working with Bhaduri, who has a background in statistics and bioinformatics, Pollen and Nowakowski began exploring how specific classes of neurons and stem cells in the developing brain contribute to normal brain growth as well as to neurodevelopmental disease, and have begun to build a comprehensive, open - source atlas of gene expression across the developing brain, which they hope will serve as a resource for other scientists.

«To the extent that psychiatric or neurological disease is localized to a specific part of the brain, we should now be considering the potentially specialized type of astrocytes regulating nerve connections in that region and their contributions to disease,» he said.

Previous research conducted on mouse models of Parkinson's disease suggested the importance of task - specific exercises on the brain.

Researchers have taken a key step towards recovering specific brain functions in sufferers of brain disease and injuries by successfully restoring the decision - making processes in monkeys.

Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

His research is based on the concept that normal brain aging and the pathogeneses of sporadic neurological diseases are not a consequence of a few single or «disease - specific «factors alone, rather they are driven by holistic events that include one's individual genetic and epigenetic condition, progression of aging, and lifestyle.

This type of targeted dosing could make it possible to treat diseases that affect very specific brain circuits, without interfering with the normal function of the rest of the brain, the researchers say.

By understanding how certain brain cells are either vulnerable or resistant to neurodegenerative diseases, the lab has also discovered specific «profiles» of vulnerable cell types, thus advancing neuroprotective strategies for Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS).

Her group has developed pre-clinical models of metastatic disease that are used to identify genes, both in the tumour cells and in the tumour micro-environment that regulate the process of metastasis to specific organs such as bone, liver, lung and brain.

SAN FRANCISCO, CA — April 29, 2012 — Scientists at the Gladstone Institutes have determined how specific circuitry in the brain controls not only body movement but also motivation and learning, providing new insight into neurodegenerative disorders such as Parkinson's disease — and psychiatric disorders such as addiction and depression.

Brain damage in Huntington's disease has a specific pattern: not all parts of the brain degenerate to the same exBrain damage in Huntington's disease has a specific pattern: not all parts of the brain degenerate to the same exbrain degenerate to the same extent.

So when AFFiRiS» Schneeberger opines that «given the mode of action of disease modifiers», an AS - clearing immunotherapy such as PD01A (or PRX002) is «really something we need to apply early in this disease» because «once the the brain cells are destroyed, getting them back is probably impossible,» he is adopting a view that is entirely reasonable — but only because it is constrained to the specific plank in the integrated platform that rejuvenation biotechnology must become.

The researchers looked at the dentate gyrus, a specific area of the brain that is critical to memory and particularly vulnerable in Alzheimer's disease, and compared the genes that were turned on and off in normal mice and a mouse model of Alzheimer's disease.

These methods led to seminal discoveries linking changes in motor behavior in Parkinson's disease with the inability of specific brain cells to be modified.

«If we could really describe how diseases change molecules in specific cells within the living brain, it might enable better drug targets to be found.»

Changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

The common and specific involvement of brain networks in clinical variants of Alzheimer's disease (AD) is not well understood.

The regional and laminar distribution in the cerebral cortex of specific neuronal populations is investigated in a variety of neurodegenerative disorders, and quantitatively compared to Alzheimer disease and control brains.

While imaging captures brain activation during specific tasks and therefore may identify general brain regions that are abnormal in diseases, it does not have that critical cell - level resolution.

SAN FRANCISCO, CA — April 26, 2012 — Scientists at the Gladstone Institutes have unraveled a process by which depletion of a specific protein in the brain contributes to the memory problems associated with Alzheimer's disease.

Huntington's disease is a devastating hereditary disorder that causes neuronal death in specific brain regions, motor functional deficits and psychological symptoms, and eventually premature death.

A feature of Alzheimer's disease (AD) is region - specific declines in brain glucose metabolism.

A recent study14 in Frontiers in Molecular Neuroscience notes that iron - restricted diets «affect brain ferritin levels, dopamine metabolism and cellular prion proteins in a region - specific manner» — effects that highlight the importance of adequate iron for general brain health and for the prevention of neurological diseases.

A 2016 study by researchers from the Buck Institute for Research on Ageing and the UCLA Easton Laboratories for Neurodegenerative Disease Research, showed that memory loss in Alzheimer's patients can be reversed, and improvement sustained, using a complex, 36 - point therapeutic personalized program that involves comprehensive changes in diet, brain stimulation, exercise, optimization of sleep, specific pharmaceuticals and vitamins, and multiple additional steps that affect brain chemistry.

I also study the immunological and neurological mechanisms involved in nutrition, herbal medicine, acupuncture, and mind - body therapies, with specific interest in the gut - brain axis in Parkinson's disease.

Symptoms of illness from breast implants vary widely but often include fatigue, muscle and joint pain, brain fog, memory loss, depression, hair loss, and symptoms associated with specific autoimmune diseases.

Region - specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain - derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas.

Topics include localization of brain function; general functions of specific brain areas; anatomy of the neuron; neurotransmission; mechanism of drug action on neurons; genetic, behavioral, and environmental influences on drug addiction; and addiction as a chronic disease.