Sentences with phrase «specific cancer markers»

The circuit, which will only activate a therapeutic response when it detects two specific cancer markers, is described in a paper published in the journal Cell.

Not exact matches

Abiraterone's ability to lower levels of prostate - specific antigen, a surrogate marker for prostate cancer, was slightly greater for patients in the low - dose with food group when measured at 12 weeks.

Take, for example, prostate - specific antigen (PSA), which is a blood serum marker used to test men for prostate cancer.

University Professor of Applied Physics Stephen Arnold and his team at the New York University Tandon School of Engineering have made a discovery that could lead to Star Trek - like biosensor devices capable of flagging the barest presence in blood of a specific virus or antibody, or protein marker for a specific cancer; or sniffing out airborne chemical warfare agents while they are still far below toxic levels.

The researchers showed that the latest approach to epidemiology worked to track both HIV infections and levels of prostate - specific antigen, a molecular marker associated with prostate cancer.

The test incorporates three specific markers that could indicate cancer and studies have shown that the combination is far more accurate than PSA alone.

All had been treated previously with at least one type of androgen deprivation therapy and had rising levels of prostate specific antigen (PSA), a blood marker for prostate cancer, and radiographic evidence their cancers were becoming resistant.

The tumour has completely disappeared in the two patients after three to four treatments and can no longer be detected neither by PET / CT imaging nor by the tumour marker PSA (Prostate - specific antigen), whose blood level is often elevated in men with prostate cancer.

Next steps for the team include identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific markers and explore possible roles for these metabolites in disease progression.

The authors believe theirs is the first study to show that mouse mammary gland tissues are sensitive to a mixture of 23 commonly used UOG chemicals, with dose - specific effects on tissue morphology, cell proliferation and induction of intraductal hyperplasias, an overgrowth of cells considered a marker for future breast cancer risk.

The cancer cell marker that Johnson and her team identified was a specific change in protein glycosylation, that is, a unique pattern of sugars decorating a protein found on the cell surface.

We are aware that at Dr. Robert Getzenberg's request, the journal Urology on Oct. 3, 2011, retracted his manuscript entitled, «EPCA - 2: a highly specific serum marker for prostate cancer.»

Cancers would be caught at their earliest stage and other stages of development, and doctors would have the necessary protein or genetic information from these captured cells to customize your treatment based on the specific markers for your cancer.

In a paper published in the journal Nanotechnology [«Static micro-array isolation, dynamic time series classification, capture and enumeration of spiked breast cancer cells in blood: the nanotube - CTC chip»], Panchapakesan's team, which includes graduate students Farhad Khosravi, the paper's lead author, and researchers at the University of Louisville and Thomas Jefferson University, describe a study in which antibodies specific for two markers of metastatic breast cancer, EpCam and Her2, were attached to the carbon nanotubes in the chip.

Each well holds a specific antibody that will bind selectively to one type of cancer cell type, based on genetic markers on its surface.

Significantly, cells with reduced mtDNA became self - renewing and expressed specific cell surface markers characteristic of breast cancer stem cells.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

Thus, as the inflammatory cascade progresses from nonatrophic gastritis through the atrophic gastritis — intestinal metaplasia — neoplastic spectrum, it was found that these 5 specific markers were statistically significant in predicting precancerous lesions in comparison to traditional risk factors (receiver operating characteristic, 0.803 vs 0.580).70 As discussed previously, intestinal - type gastric cancer is more strongly associated with the atrophic gastritis and intestinal metaplasia cascade, thus explaining the closer correlation with intestinal - type gastric cancer and the serologic biopsy than diffuse - type gastric cancer.

Professor Zhou explained: «We built a database of epigenetic markers, specifically methylation patterns, which are common across many types of cancer and also specific to cancers originating from specific tissue, such as the lung or liver.

We can envision that DAXX can serve as a precise prognostic marker in PCa and that tissue - specific shRNA delivery targeted against DAXX can be employed in the treatment of metastatic prostate cancer in patients, in particular if we discover, through additional studies, that DAXX is a marker for lethal PCa in humans.

If an oncologist does a blood test for prostate cancer, he looks for a tumor marker called prostate specific antigen or PSA.

Genetic studies have linked multiple forms of cancer with specific breeds and more will likely be discovered as genetic markers are identified.