Sentences with phrase «specific cell subtypes»

Not exact matches

Immunotherapy caused an increase in peanut - specific T cells, accompanied by a change in the distribution of T - cell subtypes over time.

The physician scientists sought to identify glioblastoma subtype - specific cancer stem cells.

A clinical trial has shown that patients with a specific molecular subtype of diffuse large B - cell lymphoma (DLBCL) are more likely to respond to the drug ibrutinib (Imbruvica) than patients with another molecular subtype of the disease.

What they found was that when they overexpress transcription factors that drive the specification of specific subtypes of neurons in other cells in C. elegans, these do not by themselves cause the cell to convert into neurons.

In culture, neural stem cells (NSCs) can readily differentiate into neuronal and glial subtypes, but their ability to differentiate into region - specific neuronal cell types is limited.

More recent work by Aggarwal and Pittenger 82 supported the feasibility of MSC - transplantation showing that MSC altered the phenotypes of specific immune cell subtypes thereby creating a tolerogenic environment.

These specific groups include T - cell subtypes (such as CD4 + CD25 + T cells), as well as a unique fraction of DCs described as semimmature DCs, all of whom were shown to possess immune - modulating properties.

Future therapies will have to be based on strategies that act by reducing or increasing the number or activity of specific subtypes of pre - and postsynaptic receptors, transporters, and ion channels, or other membrane molecules at the synapse, and by strategies that exploit the new possibilities offered by stem cell technology and targeted repair.

Researchers in NCI's Division of Cancer Epidemiology and Genetics (DCEG) integrate tissue profiling into studies examining the causes of cancer to better understand the process by which normal cells are transformed into cancer cells (carcinogenesis) and to pinpoint factors associated with risk for developing specific molecular or genomic subtypes.

One of the striking differences in outcome between our studies and work on oligodendrocyte and oligodendrocyte - precursor replacement lies in the finding that differentiation of precursor cells into a specific astrocyte subtype prior to transplantation provides a much greater level of benefit than transplantation of the precursor cells themselves.

We will study specific subtypes of cells in the eye that are more or less susceptible to glaucoma damage.

Title: Infiltrating immune cells in breast cancer subtypes Date / Time: Tuesday, April 17 2018, 8:00 am - 12:00 pm CT Author: J.L. Matta et al, Ponce Health Sciences Institute and H. Lee Moffitt Cancer Center Poster # / Location: 5698 / Section 32, Board 4 Hyperlink: http://www.abstractsonline.com/pp8/#!/4562/presentation/7977 Demonstrates the value of combining PAM50 subtype distribution with tumor immune profiling to identify biologically distinct patient populations; the combination of these signatures could be applied to the development of specific immunotherapeutics.

As our aim was to indicate general tissue specific carcinogenic properties, we used all the known subtypes of these cancers, including (1) hyper mutated and non-hypermutated colon cancers; (2) lung adenocarcinomas, large cell carcinomas, and squamous cell carcinomas (3) HER2 positive, basal, luminal A and luminal B breast cancers; and (4) hepatitis B or hepatitis C, cirrhosis or other agent causing hepatocellular carcinoma data.

Unlike NHL, which has many different subtypes, Hodgkin lymphoma is mostly distinguished by the presence of what's called Reed - Sternberg cells, or abnormal types of a specific lymphocyte.