Sentences with phrase «specific cell types within»
The team currently is exploring the cellular and molecular mechanisms underlying ischemic preconditioning using mice in which HIF - 1 activity has been knocked out in specific cell types within the heart.
https://www.hopkinsmedicine.org/
«Ideally, specific cell types within these circuits could be targeted in order to shift attention away from unhealthy cues such as high - calorie food cues.
Not exact matches
Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.
Tavazoie points out that «it is remarkable that within a single cell type, synonymous changes in genetic sequence can dramatically affect the levels of specific proteins, their transcripts, and the way a cell behaves.»
LPA is produced by a specific type of stromal cells, which forms a scaffold for lymphocytes to crawl around within the node.
One theory has been that calorie restriction slows age - related degeneration and enables more efficient tissue function by influencing the integrity and activity of adult stem cells, the precursor cells that dwell within specific tissues and give rise to the diversity of cell types that compose that tissue.
«Understanding how Cas9 is able to locate specific 20 - base - pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells,» says Doudna who holds joint appointments with Berkeley Lab's Physical Biosciences Division and UC Berkeley's Department of Molecular and Cell Biology and Department of Chemistry, and is also an investigator with the Howard Hughes Medical Institute (HHMI).
They do so by responding to a variety of time - and location - specific cues within the developing embryo that direct them to become specific cell types.
Chemical indicators have been very powerful, but are limited in scope because they can not be targeted to specific cell types or locations within a cell.
With Dr. Bill Carlezon, Dr. McCullough is investigating the cell - type specific contributions of neuron populations within the nucleus accumbens to stress related pathologies.
«It tells you about the ecosystem of the tumour», Simona says, «using fluorescent markers, we can label many specific cell types and structures within the brain in the vicinity of the tumour, and look not just at the tumour cells but how they interact with their surroundings.
They are the only means to target and manipulate specific cell types (populations) within neuronal networks in living animals.
Making use of cell and animal models, my laboratory group addresses some of the fundamental questions of how ethanol exposure injures the liver, with a goal ofidentifying the individual targets of ethanol - induced injury and the specific responses of the key cell types within the liver, as well as the integrated, organismal response to this ethanol - induced injury.
«This new work is exciting, because it shows that we can directly target genes within a specific cell type, which is important for targeted therapies,» says Hedrick, a Professor in the Division of Inflammation Biology.
During development, genes within specific cell types are turned on and off to trigger the necessary expression patterns that create a whole animal.
Oxidative Free Unstable Radicals are a specific type of molecule that can damage muscle tissue, fats, and DNA within cells.
While lymphocytes are a specific type of cell within the blood, LSA is not restricted to the blood.
On Houston's Clear Thinkers, Tom Kirkendall ponders the view of cancer as tenaciously persistent and able to regenerate after apparently disappearing — driven by a specific cell type lurking within the cancer that is capable of dormancy, growth and infinite regeneration — a cancer «stem cell» in The Cancer Sleeper cell type lurking within the cancer that is capable of dormancy, growth and infinite regeneration — a cancer «stem cell» in The Cancer Sleeper cell» in The Cancer Sleeper CellCell