The original algorithm is now freely available upon request, but Origent hopes to market programs that can be tailored to
specific clinical trial designs or even used to help doctors make more personalized predictions for their patients.
Not exact matches
But the short answer for anyone who doesn't want to buy a book is that the standard old - fashioned
clinical trial is
designed to answer a
specific question about a population with lots of different
specific characteristics.
One project involves probing Foundation Medicine's growing database of tumor profiles for
specific mutations and using that information to either
design drugs or to parse patients into
clinical trials of the company's drugs, says Pao.
«Once we understand how these drugs impact
specific cells and tissues we'll be in a position to
design clinical trials for humans,» said Kennedy.
The Scientific Review Committee (SRC) ensures that all cancer
clinical trials conducted under the auspices of the Vanderbilt - Ingram Cancer Center meet peer - reviewed standards of scientific
design, including appropriate scientific rationale,
specific aims, study endpoints, biostatistical analysis, and adequate ability to accrue patients.
In the next several years, when the laboratory process for recreating micro tumors is fast and reliable, Dr. Simeone expects to offer a Phase 1
clinical trial to
design tailored single and combination therapies, as well as experimental agents targeting
specific mutations.