«Based on our data, which is comprised of gene expression across 16 brain regions, we found that the most distinct region, i.e. the region where we observe more human -
specific differences in gene expression, is the striatum, a region involved in motor coordination, reward, and decision - making,» lead author André M. Sousa of the Yale School of Medicine and the Kavli Institute for Neuroscience told Seeker.
Not exact matches
«There was also a big
difference in gene expression of a
specific enzyme called nicotinamide N - methyltransferase.»
When the team measured
gene expression first
in the stem cells, and then re-evaluated the cells once they had become neurons, very
specific differences emerged between the cells derived from bipolar disorder patients and those without the condition.
Rather than listing
specific genes that manifest themselves differently, or are differentially expressed, between queens and workers, the team looked for
genes with similar
expression patterns across samples that may be involved
in maintaining the structural, behavioural and functional
differences observed between queens and workers.
It's the first time scientists have shown
in selectively bred animals that the propensity for addiction is linked to
differences in expression of
genes for
specific molecules
in a
specific brain region.
Because PMI dependent
expression changes are largely tissue -
specific, they could confound tissue differential
gene expression since the observed effects could be caused by differential response to PMI rather than by
differences in tissue biology.
Sex
differences describe biology - linked
differences between women and men, which are caused by
differences in sex chromosomes, sex -
specific gene expression of autosomes, sex hormones, and their effects on organ systems (Figure 1)(1, 3).
Recently, a large - scale microarray study characterized
gene expression differences between current, former, and never smokers [5], and identified
specific genes related to xenobiotic functions, anti-oxidation, cell adhesion and electron transport to be more highly expressed
in current smokers relative to never smokers.
In this activity students analyze data on the expression of the tb1 gene and use it to formulate an explanation as to how a specific difference in the corn version of the gene explains the phenotype of less branchin
In this activity students analyze data on the
expression of the tb1
gene and use it to formulate an explanation as to how a
specific difference in the corn version of the gene explains the phenotype of less branchin
in the corn version of the
gene explains the phenotype of less branching.