Sentences with phrase «specific driver mutations»

While mutational burden has important implications for treatment with immunotherapy, the presence of specific driver mutations is also of major therapeutic relevance (Table 3).

Not exact matches

In partnership with a patient's physician, we can tailor specific treatments to match an individual's driver mutations and disease.

The Cancer Gene Census (CGC) database contains 547 such gene across various cancer types.5 Remarkably, few driver genes having specific point mutations appear to be sufficient to rewire signalling networks in cancer, 1 which at the same time shows that — at least from the mutational side — cancer does not consist of an «infinite» number of different diseases, and in many cases treatment options targeted against driver genes might be transferred from one case to the next.