In this study, published in the journal Cell Reports, and led by Dr. Esteban Ballestar (IDIBELL), the comparison of the epigenetic profiles between dendritic cells and myeloid - derived suppressor cells has allowed them to identify the existence of
specific epigenetic alterations that associated with the development of myeloid - derived suppressor cells as a result of exposure to prostaglandin E2.
Interestingly, especially the placenta shows many sex -
specific alterations, also in regard to
epigenetic mechanisms, which might truly have huge impact on complications in and after pregnancy.