Sentences with phrase «specific epigenetic marks»
Alternatively, they documented a genomic imprinting caste determination system in termites, in which queen - and king - specific epigenetic marks antagonistically influence the sexual development of offspring and thus determine their caste fate.
http://amnat.org/
These 45 variants are significantly enriched for protein - coding changes (n = 13), direct disruption of transcription - factor binding sites (n = 3), and tissue - specific epigenetic marks (n = 10), with the last category showing enrichment in specific immune cells among associations stronger in Crohn's disease and in gut mucosa among associations stronger in ulcerative colitis.
Not exact matches
Cell processes are also determined by the chemical labeling (or marks) and specific spatial organization of our genomes, which are epigenetic characteristics — that is, nongenetic but nonetheless inheritable traits.
The specific pattern of epigenetic marks in a cell type specifies identity and this epigenetic control is vital to what makes our cells different, for example a skin cell from a liver cell, when they all contain the same genetic instructions.
This happens by epigenetic silencing of the other copy, where specific marks on the DNA carry a memory of whether a gene sitting on a copy of a chromosome came from the sperm or the egg.
The overall goal of the core is to provide support to investigators interested in characterizing the interactions of post-translational modifications of histones (epigenetic marks that define a chromatin state or Epigenome) or transcription factors at specific genomic loci or genome - wide (Cistrome).
The pluripotent population is characterized by a high degree of plasticity in chromatin structure [3], and lineage specific transcription factors show bivalent chromatin epigenetic marks characteristic of both suppression and inactivation [4].