Sentences with phrase «specific epigenomic»
Our objective is to generate a resource that facilitates research into human immune - related diseases by creating a comprehensive database of cell type - and allele - specific epigenomic and transcriptomic data for the immunology community.
http://www.lji.org/
Currently, enhancers can be identified through chromatin - based assays, such as ChIP - seq, which predict enhancer elements indirectly based on the enhancer's association with specific epigenomic marks, such as transcription factors or molecular tags on DNA - associated histone proteins.
Not exact matches
«This is exactly the technology you could use to look for epigenomic changes in specific cell types,» says Martienssen, who is also on the International Human Epigenome Consortium's steering committee.
The researchers used tools of epigenomic analysis to trace the specific epigenetic switches controlling each of thousands of genes in both mouse and human retinal cells as the cells progressed through development.
These comprehensive epigenomic profiles enable us to understand the cause, function, and consequence of cancer - specific epigenetic changes.
In the past few years, functional genomics, epigenomics, and regulatory genomics datasets have begun to drive the formulation and testing of mechanistic hypotheses that link specific genetic variants within implicated loci to human traits and phenotypes.