The analysis by our unique collaboration indicates that the cancer risk in these relatively benign early lesions is determined by the number of abnormal clones that has been established in the Barrett's mucosa, rather than by
specific gene abnormalities.»
Not exact matches
For instance, says Korenberg, the data could help scientists to link
genes that seem important in certain mental disorders, such as schizophrenia or autism, to
specific brain - wiring
abnormalities.
Through this technology, scientists obtained stem cells from individuals with a genetic
abnormality that confers increased susceptibility to schizophrenia, and they observed deficits during nerve development that could be traced to a
specific gene called CYFIP1, which helps maintain a nerve cell's structure.
The expense and effort are increased by the FDA requirement that any company applying for approval of a drug targeted against a
specific gene - driven
abnormality must also produce a diagnostic test for that
abnormality.
«A prominent and well - characterized feature of AD is progressive, region -
specific declines in the cerebral metabolic rate of glucose (CMRglc)-LSB-...] Carriers of a common Alzheimer's susceptibility
gene [APOE Ɛ4] have functional brain
abnormalities in young adulthood, several decades before possible onset of dementia.