Sentences with phrase «specific gene expression programs»

This line of research will reveal how developmental signaling pathways interact with chromatin to establish specific gene expression programs.

How developmental signaling pathways interact with chromatin to establish and maintain lineage - specific gene expression programs remains unclear.

Not exact matches

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.»

«We are truly excited about the RNA transcript data and the map of gene expression that we now have for 27 different organ - specific tissues», says Professor Mathias Uhlén, Program Director of the Human Protein Atlas.

Activation of a TGF --LCB- beta -RCB-- Specific Multistep Gene Expression Program in Mature Macrophages Requires Glucocorticoid - Mediated Surface Expression of TGF --LCB- beta -RCB- Receptor II.

Now researchers at UC San Francisco have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain, making available new insights into how specific cells and gene networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability and schizophrenia.

cell types may have evolved through cooption of temporal gene regulation in an ancestor whose different phases were converted into germ - and soma - specific expression programs.

These results suggest that V. carteri cell types may have evolved through cooption of temporal gene regulation in an ancestor whose different phases were converted into germ - and soma - specific expression programs.

The activated AHR / NuRD complex altered the expression of differentiation - specific genes that control the first two developmental decisions without affecting the pluripotency program.

Now not only can we order a test in the public domain which charts out DNA and the specific genes we carry, but we can learn how you can significantly influence gene expression called epigenetics, and thus improve your health with a personalized nutrition program and lifestyle choices.