Sentences with phrase «specific gene families»

Instead, the evolution of the octopus genome was likely driven by the expansion of a few specific gene families, widespread genome shuffling and the appearance of novel genes.

Nearly three - quarters of the 1,286 animal - specific gene families arose by gene duplication on the metazoan stem (Supplementary Note 9).

Similarly, there are eumetazoan, eumetazoan sensu stricto and bilaterian genomic synapomorphies, as well as sponge - specific gene families (for example, kinases, see Supplementary Note 8).

Although it shows no sign of the whole - genome triplication identified in Solanaceae species such as tomato, the genome includes several species - specific gene family expansions, among them N - methyltransferases (NMTs) involved in caffeine production, defense - related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis.

Not exact matches

If you have a strong family history of breast cancer or other cancers, your doctor may recommend a blood test to help identify specific mutations in BRCA or other genes that are being passed through your family.

And this family of proteins is shaped by the specific genes a person carries.

Of note, these gene families were most commonly found to have specific protein features gained from their eukaryotic hosts.

EPFL scientists have now taken the first extensive look at a family of ~ 350 human proteins, showing that they establish a complex interplay with transposable elements to create largely human - specific gene regulatory networks.

NIPD for single gene disorders in a fetus is diagnostic, as it targets specific genetic changes present in a high risk family.

The researchers» next step is to use the genomic data they collected from the families — including full genome sequences and gene expression data — to begin identifying the specific genes that contribute to risk for bipolar disorder.

We still don't know enough about how these molecules influence specific genes, entire gene families, or biochemical reaction pathways.

By also examining this genetic region in two other families with similar disorders, the researchers were able to pinpoint a mutation in a specific gene, NT5E, which is involved in breaking down calcification in the arteries.

Researchers suspect an autoimmune reaction is to blame because many people who develop narcolepsy — and just about everyone with the vaccine - associated form — have a specific variant in a gene in the HLA family, which helps the body distinguish its own proteins from those made by microbial invaders.

To say there's some sort of heritable component to a trait tells us something can be passed on in a family that can contribute to performance, but what are the specific genes?

There's also a genetic component: The condition, which can occur at any age, often runs in families and specific gene variants have been linked to it.

When they screened the KE family to see if some carried a defect in this gene, all affected members turned out to share a specific mutation that apparently rendered FOXP2 inactive, the group reports in the 4 October issue of Nature.

«The exciting thing here is the expansion of a gene family associated with expression in specific neurons,» says Evan Eichler, a geneticist at the University of Washington, Seattle.

«This time we sequenced the families for this specific CLP1 gene mutation and all had it,» said Karaca.

«This prototype paves the way for constructing a family of reporter genes, each with proteins tailored to have a specific radiofrequency response,» says MRI researcher Assaf Gilad, Ph.D., lead author of the study.

The illness runs in families, and is known to have a strong genetic component, though efforts to identify the specific gene or genes that predispose a person to schizophrenia have so far been inconclusive.

Many species - specific genes, especially large surface antigen families, occur at nonsyntenic chromosome - internal and subtelomeric regions.

Finally, the authors mention that genes specific to hypnozoite forming parasites mainly belong to variant multigene families and unlikely to be relevant for hypnozoite formation.

Although we have seen that sponges and eumetazoans share many common pathways related to morphogenesis and cell - type specification, there are notable genomic differences, including different microRNA assemblages46, lineage - specific domains and domain architectures, and the differential expansions of gene families.

Out of 4,670 pan-metazoan gene families defined by clustering sponge and eumetazoan peptides, 1,286 (27 %) seem to be metazoan - specific (see Supplementary Note 9.2).

Because the gene and protein sequences of both enzymes are known, «now we can take the whole repertoire of drugs and see how they bind to PGHS - 1, predict how they might bind to PGHS - 2, and try to fashion whole new families of drugs that would be highly specific for one form or the other,» Garavito said.

HDACs are a family of enzymes which, amongst other things, influence access to DNA and are involved in whether specific genes, such as tumor suppressing genes, are expressed or not.

By looking at your specific allelic variants of your HLA family of genes, genetic testing can help you determine if genetics play a role in your gluten sensitivity.

In addition, True Health offers the ability for clinicians to test individual, single - site genes as needed for patients with specific mutations known in the family.

A woman with a strong family history of ovarian cancer who tests negative for a specific gene mutation is still at a higher risk for ovarian cancer.

Dallas Cowboys Announce Art Program for New Stadium 14 Artists Creating Site - Specific Works for Cowboys Stadium, Including Mel Bochner, Olafur Eliasson, Teresita Fernandez, Matthew Ritchie, Lawrence Weiner Unprecedented Art Program Features Monumental Commissions At Key Locations Throughout Cowboys Stadium Arlington, TX (August 7, 2009)-- Dallas Cowboys owners Gene and Jerry Jones, along with their family, today announced the Dallas Cowboys Art Program, an ongoing initiative to commission contemporary artists to create monumental, sitespecific installations for the recently completed Cowboys Stadium.

Her OB - GYN tested her for two specific gene mutations after the plaintiff notified her physician of a family history of cancer.