For example, centenarians not only have retarded biological ages, they're also more likely to carry
specific gene variations (called single nucleotide polymorphisms, or SNPs) that protect against disease.
Not exact matches
In the case of homosexuality we potentially are talking about randomly occurring
variations of a a
specific gene that would seem to occur with regularity.
We have identified hundreds of genetic
variations associated with autoimmune diseases that appear to affect the activity of
genes in
specific regions of the genome, pointing to biological pathways that may be involved in disease and which, ultimately, may be treatable with medication.»
Individuals who had a particular
variation in a
specific gene (platelet derived growth factor D; PDGFD) had a markedly increased risk of adrenal suppression, both in the children with asthma and adults with COPD.
Then, they examined the bacterial DNA, looking for patterns or
variations in the microbes»
genes that would help them identify
specific strains of bacteria.
Focusing on
specific genes or regions is an especially good strategy for taxonomy projects, where
variation in a few
genes is often sufficient to place an organism on a phylogenetic tree.
They found men with a
specific variation in the well - known TCF4
gene have a higher risk of disease, while women with
variations in one of the newly identified
genes, LAMC1, have an increased risk.
People with a
specific variation in the CLOCK
gene have more migraines under financial stress.
Genes with mammoth - specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Ar
Genes with mammoth -
specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including
genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Ar
genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal
variations in day length in the Arctic.
In addition to identifying a
gene that raises risk for colorectal cancer from eating red or processed meat, the study — the first to identify the interactions of
genes and diet on a genome - wide scale — also reveals another
specific genetic
variation that appears to modify whether eating more vegetables, fruits and fiber actually lowers your colorectal cancer risk.
If
variation of the sequence of a
specific gene is greatly reduced in modern versions, this is considered a sign that it was shaped by the selective pressures of domestication.
The researchers first employ a process termed «mutagenesis» to create random
variations in a
specific gene.
«We're confident that applying this same approach to a lot of new data will help us discover additional genomic
variations and identify
specific genes that play a role in schizophrenia and other psychiatric conditions.»
By analyzing
variation in a
specific bacterial
gene in his samples — the greater the variability, the higher the variety of species — Fierer found that deserts contained up to twice as many bacterial species, roughly 10,000 per 10 square meters, as did acidic rain forest soils.
With 1 million probes, it identifies microbes based on
variations of a
specific gene, with no culturing needed.
This methodology contrasts with scans for outlier genomic regions among modern breeds (35), which can, at best, identify
genes that are
specific to breeds, in the absence of knowledge of the predomesticated genetic background and sources of
variation.
Everyone has the same
genes, but
variations in them influence whether or not a person gets a
specific disease.
The researchers in this study have pinpointed
variations in a
specific gene — MC1R — that are directly related to how old people appear to others.
Studying a
specific type of genetic
variation in the DNA sequences of wolves and domestic dogs - called Single Nucleotide Polymorphisms (SNPs)- the scientists identified the transfer of dog
gene variants into wolf genomes.
These broad associations with complexity are evidently superimposed on notable lineage -
specific variation as seen in Fig. 4 (for example, serine protease
gene loss in C. elegans, and voltage-gated ion channel expansion in Paramecium).
Home > Press > Single - cell mRNA cytometry via sequence -
specific nanoparticle clustering and trapping: Cell - to - cell
variation in
gene expression creates a need for techniques that can characterize expression at the level of individual cells
This paper provides the most comprehensive analysis so far of
variation in
specific EBV
genes relevant to these diseases and proposed EBV vaccines.
However,
gene variations, the presence of strain -
specific genes, and the occurrence of plasmids in strain GP59 could affect the expression pattern of these common
genes.
The reason for all the types of mutations is
variations in the
specific genes passed on from each parent.
The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait
variations that are caused by external or environmental factors that switch
genes on and off and affect how cells read
genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a
specific health issue even though they have a SNP mutation.
The increased power provided by looking for
specific gene candidate
variations rather than linked markers will aid the identification of epilepsy risk factors, perhaps leading to development of DNA tests to enable breeders to select against such risk factors.
This study will test the hypothesis that much of the morphological
variation between individuals is due to a
specific type of mutation that involves repeated sequences in
genes.
Remember that alleles are different
variations of the basic
genes that are at
specific positions on the chromosome, and determine colors sown in the integument.