Sentences with phrase «specific human pathologies»
The unit study macromolecules that are central in basic processes of cellular life, as well as for specific human pathologies.
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«The presence of amyloid and tau pathology in aged chimpanzees indicates these Alzheimer's disease lesions are not specific to the human brain as generally believed,» Hof continued.
Specific Aim 2: Having utilized mutant mice to identify the key players in AMD pathology from Specific Aim 1, we will develop and test molecules that target either the anaphylatoxins or the MAC, or both, in the context of practical therapies that can be utilized in humans.
The co-incidence of these 2 pathologies occurs also in humans suggesting a common pathological mechanism moving across the gut - joint axis, with TNF signals acting on specific cell types directing pathogenesis at two different locations.
ESRP1 is central to intestinal barrier integrity in mice and humans and alterations in ESRP1 function or expression contribute to intestinal pathology, partly through modified expression of ESRP1 - specific GPR137 isoforms.