Although this problem can, to some extent, be addressed by the use of reporter constructs (e.g. Diptericin - LacZ) that provide quantitative or visual read - outs from
specific immune response genes, we still lack the ability to follow bacterial infections in real - time in the critical early stages of infection.
Not exact matches
Glk1 is a transcription factor, meaning it binds to
specific regions of DNA and activates
genes involved in cell death and other plant
immune responses.
Researchers at the U.S. Military HIV Research Program (MHRP) tested whether
specific variants of
immune response genes called HLA were associated with greater protection against the virus.
Specific variants of one or both of these
genes, which play a role in the body's
immune responses, have been found in 74 percent of AMD patients who were studied.
Using
gene - targeted mice and human cells that lack
specific components of the
immune system, a better understanding of the
immune response to DENV and ZIKV is critical for developing much - needed vaccines and antivirals.
Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of
genes coding for junctional proteins by Q - real - time PCR;
immune response by in - vitro antigen -
specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.