Our AST - VAC immunotherapy programs employ three common elements of dendritic cells, telomerase antigen, and the LAMP signal sequence to stimulate robust and
specific immune responses to cancer cells (Figure 1).
Not exact matches
Dr. Gnjatic's research focuses on human antigen -
specific immune responses to tumor antigens, in an attempt
to define new targets for the development of
cancer immunotherapies, assess the efficacy of these immunotherapies, and learn why they may fail.
One of the immunotherapeutic approaches that has been explored thus far relies on the use of monoclonal antibodies that specifically target a protein present on the surface of prostate
cancer cells called prostate
specific membrane antigen (PSMA)
to elicit an anti-tumor
immune response and control the
cancer.
However, despite this success, the use of immunotherapy remains limited by the scarcity of tumor -
specific antigens — substances that can trigger an
immune system
response to a particular type of
cancer.
A personal
cancer treatment vaccine that targets distinctive «neoantigens» on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana - Farber Cancer Institute and the Broad Institute of MIT and Ha
cancer treatment vaccine that targets distinctive «neoantigens» on tumor cells has been shown
to stimulate a potent, safe, and highly
specific immune anti-tumor
response in melanoma patients, report scientists from Dana - Farber
Cancer Institute and the Broad Institute of MIT and Ha
Cancer Institute and the Broad Institute of MIT and Harvard.
Dr. Khleif's research interest is in identifying new and improved strategies
to enhance
specific immune response against
cancer for preventive and therapeutic intent.
Researchers are studying how
to use tumour -
specific neoantigens in vaccines
to help the body mount an
immune response targeted at the
cancer.
Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these ant
Cancer vaccines are designed
to stimulate an
immune response against tumor -
specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these ant
cancer cells bearing these antigens.
Therapeutic vaccines are designed
to elicit an
immune response against tumor -
specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these antigens.
Therapeutic
cancer vaccines are designed
to elicit an
immune response against tumor -
specific or tumor - associated antigens, encouraging the
immune system
to attack
cancer cells bearing these antigens.
Cancer vaccines are designed
to elicit an
immune response against tumor -
specific or tumor - associated antigens.
Over the past few years, they have extended their research
to understand how products of cellular necrosis and the innate
immune responses they induce affect the tumor microenvironment, with a
specific focus on ovarian
cancer.