Sentences with phrase «specific immune system response»

Not exact matches

We found that when it comes to cutaneous immunity — specific to skin — the immune system was being obstructed by skin cells that were too prone to producing inflammation responses.

These cells, in turn, instruct factor - VIII — specific immune cells to become tolerant to the coagulation protein, resulting in suppression of misdirected antibody responses to the replacement therapy — all without affecting the rest of the immune system.

«Adenosine deaminase may help the immune system fight HIV on its own: Adenosine deaminase enhances anti-HIV-1 specific immune responses by reducing the action of cells that impede HIV - specific defenses.»

A study published in PLOS NTDs examining the immune response to one of them in Haitian adults finds that while the first vaccine round elicits a strong cholera - specific response in the mucosa (the first point of contact with the cholera pathogen), the booster dose after 2 weeks does not appear to stimulate the immune system further.

However, despite this success, the use of immunotherapy remains limited by the scarcity of tumor - specific antigens — substances that can trigger an immune system response to a particular type of cancer.

«Our results clearly demonstrate a significant, although unexpected, role for specific gut bacteria in enhancing the immune system's response to melanoma and possibly many other tumor types,» said study director Thomas Gajewski, MD, PhD, professor of medicine and pathology at the University of Chicago.

The group also has experience in the creation of custom panels for the analysis of pathogen specific immune responses with focus on innate and adaptive arms of the immune system.

This is a powerful system to screen polyfunctional CD4 + and CD8 + T - cell - specific immune responses.

If sufficient 1,25 - dihydroxyvitamin D is produced, it may exert paracrine effects on surrounding T lymphocytes, thereby regulating the tissue - specific immune responses.10 Some support for this hypothesis comes from recent experiments showing that mice fed diets high in vitamin D had significantly fewer clinical and pathological signs of EAE than mice fed a vitamin D — deficient diet.37 Central nervous system levels of 1,25 - dihydroxyvitamin D, but not blood levels, were higher in supplemented mice than in vitamin D — deficient mice and correlated inversely with disease severity.

Charles Janeway introduces the hypothesis that «components of the innate [immune] system, especially antigen - presenting cells such as DCs, required the microbial stimuli contained in [adjuvants] to become activated and acquire the capacity to induce productive responses from antigen - specific lymphocytes.

Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair pathway 8.55 Karol Kaiser Wnt secretion during nervous system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure

Lupus makes the immune system unable to differentiate between antigens (a substance capable of inducing a specific immune response) and healthy tissue.

Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

The immune system can also form long - lasting memories specific to the disease for faster response times should the disease re-emerge.

Therapeutic cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

The mission of the ITN is the development of new immune tolerance therapies — highly specific treatments that reprogram the immune system to inhibit disease - causing immune responses while keeping beneficial, disease - fighting immune responses intact.

The laboratory is defining in chemical terms the specific structures (epitopes) that the immune system recognizes, and uses this knowledge to measure and understand immune responses.

This surface coat is a monolayer of millions of variant surface glycoproteins (VSG) that protect the parasite from the innate immune system and, through antigenic variation, against the specific host immune response.

How do immune system specific cells react and behave in response to infections and other perturbations?

Using gene - targeted mice and human cells that lack specific components of the immune system, a better understanding of the immune response to DENV and ZIKV is critical for developing much - needed vaccines and antivirals.

Natural killer (NK) cells, the «rapid response» cells of the innate immune system, can kill virally infected cells and thereby slow down an infection until antigen - specific and clonally - expanded cytotoxic T cells can be recruited to finish the job.

A leukocyte activation test identifies food items which induce release of DNA by innate immune peripheral blood leucocytes Irma Garcia - Martinez, Theresa R. Weiss, Muhammad N. Yousaf, Ather Ali † and Wajahat Z. Mehal † † Contributed equally Published in BioMedCentral, Nutrition and Metabolism View Publication Abstract Background Leukocyte activation (LA) testing identifies food items that induce a patient specific cellular response in the immune system,...

Inflammation from eosinophilic asthma occurs as part of an allergic or immune system response, which releases a specific white blood cell called eosinophils.

Vaccines are inactivated or altered live disease agents that cause the immune system to produce a protective response specific to that disease.