Due to these physiopathological complexity and heterogeneously, one of the major requirements for a successful therapy is the design of a multifunctional nanomedicines that is able to selectively attack
specific markers from tumor and stroma cells.
The team selected cells with cardiac -
specific markers from cultures of HES cells.
Not exact matches
Some teams use zonal and have
specific man
marker for a dangerous player... shearer, Carroll etc who did or can excel at putting the ball in the back of the net
from a corner.
Scientists at CNRS, Aix - Marseille Université and AP - HM have identified a cerebral
marker specific to autism that can be detected by MRI and is present as
from the age of two years.
He and his colleagues extracted mitochondrial DNA
from the samples and screened it for
specific markers, using a technique called restriction mapping.
Cancers would be caught at their earliest stage and other stages of development, and doctors would have the necessary protein or genetic information
from these captured cells to customize your treatment based on the
specific markers for your cancer.
Some FGF2 - treated cells also expressed
markers for the rhombic lip — the structure
from which granule cells develop and migrate, and a
marker specific to migrating granule precursors by week seven.
Expanding
from their previous studies with mice, the researchers first established that under
specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of
markers for the cerebellar plate neuroepithelium — the part of the developing nervous system
specific for the cerebellum — within five.
Thus, as the inflammatory cascade progresses
from nonatrophic gastritis through the atrophic gastritis — intestinal metaplasia — neoplastic spectrum, it was found that these 5
specific markers were statistically significant in predicting precancerous lesions in comparison to traditional risk factors (receiver operating characteristic, 0.803 vs 0.580).70 As discussed previously, intestinal - type gastric cancer is more strongly associated with the atrophic gastritis and intestinal metaplasia cascade, thus explaining the closer correlation with intestinal - type gastric cancer and the serologic biopsy than diffuse - type gastric cancer.
Asialoglycoprotein receptor 1 is a
specific cell - surface
marker for isolating hepatocytes derived
from human pluripotent stem cells.
For the detection of
specific antigens, the following primary antibodies were used: mouse monoclonal anti-Tuj1 (Covance, Princeton, NJ, USA) as a neuronal
marker, rabbit anti-L1 (kindly provided
from Dr. Asou)[52] and rat monoclonal anti-L1 (Millipore, Billerica, MA, USA) as granule cell
markers, rabbit anti-calbindin D28K (Millipore) as a Purkinje cell
marker, and rabbit anti-glial fibrillary acidic protein (GFAP, DAKO, Denmark) as an astrocyte
marker.
By means of a non-obese diabetic / severe combined immunodeficiency disease (NOD / SCID) xenotransplant assay in combination with
specific cell surface
markers (CD44 + CD24 - / low), CSCs were enriched
from metastatic and primary breast tumors and were shown to have the ability to reestablish tumor heterogeneity after transplantation [1].
Professor Zhou explained: «We built a database of epigenetic
markers, specifically methylation patterns, which are common across many types of cancer and also
specific to cancers originating
from specific tissue, such as the lung or liver.
(A) Retinal section obtained
from a P150 eye immunostained with human -
specific nuclear
marker.
GFAP, a class - III intermediate filament, is a cell -
specific marker that, during the development of the central nervous system, distinguishes astrocytes
from other glial cells.
These cells often have virus -
specific T cell receptors, as well as other surface
markers that distinguish them
from their youthful counterparts, and they are thought to play a major role in the decline of the immune system with age.
As seen in cells dissected
from colonies, significant numbers of cells coexpressed lineage
specific markers along with pluripotency genes.
The antibodies listed above in the immunocytochemistry section were also used on eye sections together with a cocktail of antibodies generated against human -
specific markers (HSM) to identify human cells (the Oka blood group antigen, mouse TRA -1-85, 1 ∶ 10 (a kind gift
from Peter Andrews, University of Sheffield, Sheffield, UK) together with mouse human nuclear antigen, 1 ∶ 1000, Millipore).
We suggest correct identification of the origin of these cells (using human
specific markers, which define cell membranes) is essential in order to distinguish viable donor cells
from host inflammatory cells which have engulfed transplanted cells.
Germ cell
specific markers are also expressed in embryoid bodies derived
from human ES suggesting the presence of PGC's, so I am developing methods to enhance their formation and isolation.
«Given the high content of certain
specific polyphenols in the juice blend, the increased antioxidant protection [in the body] after consumption of the juice blend, and the anti-inflammatory capacity in vitro, further research is warranted to evaluate whether juice blend consumption may provide reversal of risk
markers in subjects with conditions such as arthritis, obesity, chronic viral diseases, cardiovascular disease and compromised cognitive function, as well as other conditions associated with chronic inflammation,» wrote lead author Gitte Jensen
from Holger NIS Inc., a contract research laboratory.
The products, which range
from around $ 25 to a couple hundred bucks, comb through your genome looking for
markers linked to
specific traits.
This test does not determine breed type, rather, it identifies
specific gene
markers that are inherited
from both parents.
This test does not determine breed type, rather, it identifies
specific gene
markers that are highly variable and inherited
from both parents.
With regard to familial loading and temperament, it is important to distinguish general risk factors (Frustration)
from dimension -
specific risk factors (familial loadings, Effortful Control, Fear), and direction
markers that act as pathoplastic factors (Shyness, High - Intensity Pleasure, Affiliation)
from both types of risk factors.