Sentences with phrase «specific markers of disease»

The lack of specific markers of disease and the fact that the CFS diagnosis is controversial imply that the level of diagnostic accuracy and adherence to international criteria are likely to be variable.

Not exact matches

In a description of a sleep disorder known as RBD, in which patients enact their dreams through movement, he notes that a deficiency of dopamine (a specific brain neurotransmitter) is one key marker of Parkinson's disease.

The team's laboratory research will also focus on expanding the sensing capability of the bandage to other treatment - related parameters — such as pH, bacterial load, oxidative states and specific disease markers — and incorporating an on - demand drug release capacity.

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

Physicians will monitor the patient's levels of prostate specific antigen (PSA), a marker of disease progression.

«Our findings show that a specific genetic marker (known as allele * 2 of the HS1, 2 A enhancer region) influences not just disease activity in RA patients, but also response to therapy in the early stages of their disease,» said lead investigator Dr Gabriele Di Sante of the Institute of Rheumatology and Related Sciences, Catholic University of the Sacred Heart, Rome, Italy.

A specific genetic marker influences response to therapy in the early stages of RA; a link thought to be due to the gene activating a cell - signalling protein involved in the inflammatory disease process.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

Discovery of novel disease - specific and membrane - associated candidate markers in a mouse model of multiple sclerosis.

Since different antibodies are markers of different diseases, this could become a very specific weapon in the clinician's hands.»

By means of a non-obese diabetic / severe combined immunodeficiency disease (NOD / SCID) xenotransplant assay in combination with specific cell surface markers (CD44 + CD24 - / low), CSCs were enriched from metastatic and primary breast tumors and were shown to have the ability to reestablish tumor heterogeneity after transplantation [1].

The first of its kind, the study provided specific markers to distinguish different disease states in asthma and paved the way for investigating the role of epigenetic mechanisms in other immune - mediated disorders and infectious diseases.

It brings together patients, clinicians and researchers to accelerate the development of individualized asthma treatments based on patient - specific disease markers.

Notably, NfL is not specific for HD and has also been proposed as a marker to track the progression of other neurodegenerative diseases, including Alzheimer's and ALS.

«Given the high content of certain specific polyphenols in the juice blend, the increased antioxidant protection [in the body] after consumption of the juice blend, and the anti-inflammatory capacity in vitro, further research is warranted to evaluate whether juice blend consumption may provide reversal of risk markers in subjects with conditions such as arthritis, obesity, chronic viral diseases, cardiovascular disease and compromised cognitive function, as well as other conditions associated with chronic inflammation,» wrote lead author Gitte Jensen from Holger NIS Inc., a contract research laboratory.

Cardiac specific c - reactive protein is a marker of inflammation in the blood vessels, now thought to be a serious risk factor in heart disease.

Specific patterns of markers are used to predict the presence or absence of a disease mutation.