Sentences with phrase «specific mechanisms of cancer»
Not exact matches
The program works by connecting computer - generated drug profiles — including mechanisms of action, clinical efficacy, and side effects — with information about how a molecule may interact with human proteins in specific diseases, such as ovarian cancer.
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She is investigating the role of glycosylated molecules in tumor progression and metastasis, tissue - and species - specific expression of lectin receptors that play a role in regulating host innate immune responses and inflammation, and the immunological mechanisms underlying chronic inflammation and cancer development.
The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patCancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patcancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.
«Further research is needed to understand mechanisms whereby smoking may increase colorectal cancer - specific mortality and determine if quitting smoking after diagnosis lowers the risk of colorectal cancer - specific mortality,» the authors conclude.
Their findings could help to improve breast cancer prevention by targeting these specific biological mechanisms with cancer therapies in at risk patients and potentially lead the way for a new strategy for the use of preventative treatments.
«GECCO aims to continue to discover additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle risk factors, including biomarkers as well as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer risk.
No previous studies have investigated the direct effect of sugar consumption on the development of breast cancer using breast cancer animal models or examined specific mechanisms, she added.
Species - specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone.
Dissecting these interactions with a combination of cell - biology and systems biology approaches should allow uncovering the tissue specific control mechanisms that are defective in cancer.
Specific translational studies include: Molecular mechanisms of migration contribute to metastasis and subsequently thought to be central to the cancer progression poor clinical outcome for cancer patients.
More than half of mammalian genes generate multiple messenger RNA isoforms that differ in their 3 ′ untranslated regions (3 ′ UTRs) and therefore in regulatory sequences, often associated with cell proliferation and cancer; however, the mechanisms coordinating alternative 3 ′ - UTR processing for specific mRNA populations remain poorly defined.
The mechanism of rainbow plasmonic nanobubbles significantly improves the selectivity of bubble generation in specific target cancer cells compared to non-specific stromal (non-cancer) cells and can therefore provide the cell level selectivity needed for diagnosis and therapy.
Given that fermentation in the colon is the mechanism for achieving colorectal cancer protection, via the specific contribution of n - butyrate to reduction of proliferation and induction of differentiation of the mucosal cells (Cummings 1981), it is probable that dietary manipulations which slow the fermentation rate of [RS] and dietary fiber would be of benefit in cancer protection in the distal colon and rectum.»
No previous studies have investigated the direct effect of sugar consumption on the development of breast cancer using breast cancer animal models or examined specific mechanisms, she added.
Before going into the merits of the specific nutritional requirements of dogs with cancer, it would be useful to examine the various mechanisms by which cancer causes — in the long run — such a debilitating loss in body condition.