Sentences with phrase «specific mechanisms of change»

Modern predictive models require data about the specific mechanisms of change too, in order to better project the response to climate change.

Not exact matches

Furthermore, clipping or genetically ablating wings from flies prevented the protective effects of DR on lifespan, demonstrating a critical role for the observed increase in physical activity in determining lifespan upon DR. To further elucidate the mechanisms by which changes in DR mediates changes in metabolism we are identifying and characterizing various tissue specific modulators of fat metabolsm

«Future studies are focusing on the molecular mechanisms underlying the ageing - related changes in skeletal muscle and the specific effects of HRT on the structure and function of the dominant protein in skeletal muscle, called myosin, which generates force and movement.»

Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the pathways of the virus.

This study is one of the first randomized, controlled trials to look at the specific mechanisms related to change in PTSD symptoms that might be positively impacted by yoga practices.

The signature feature of FOI is its commitment to the ongoing construction of theories of change that are grounded in science and drive the design of explicit strategies focused on specific causal mechanisms to produce breakthrough gains on important outcomes.

- the game's shading mechanism has changed, which allows for increased gear texture quality - all graphical aspects and programming mechanisms have been built up from scratch for this sequel - maximum resolution is 1080p in TV mode - a bigger focus for Nintendo was the 60 frames per second - occasionally the resolution will be scaled down when there is too much ink displaying on the screen - Nintendo reduced the CPU load and refined the way to use CPU power effectively to maintain 60 fps in all matches - weapons were tweaked to let players be more creative by thinking about unique weapon characteristics and their best uses - weapons are designed to be effective when they are used during the right occasion - Special weapons are stronger than the original ones when used in the right situation, but weaker otherwise - the damage and effect of slowing down your movement when you step in the opponent's ink are reduced from original - you can jump up in rank if you're good enough, but only up until S - you can't jump up from C, B or A to S + - when you win battles in Ranked mode, the Ranked meter fills and your rank goes up when its fully filled - when you lose a battle, the gauge does not decrease, but the meter starts to crack - once the meter reaches its limit, it breaks - when the meter breaks, you have to start over again from the beginning or from a lower rank - highest rank is still S +, but if you fill up the Ranked meter, you get numbers after the alphabet such as «S +1», «S +2» and so on - maximum number is «S +50», but this number will not be displayed to your opponent - you are the only one to see it, and you can check it on your own status screen - Ranked Power is calculated by an algorithm to measure how strong each player is with minuteness - this will determine if a player's rank is worthy of receiving a big jump (like from «C» to «A»)- Ranked Power has no relation to your splat rate, and is more tied into to how well you lead your team to victory - you won't drop off more than one rank even if you play poorly - stage rotation time was changed to two hours - this was done because the devs expected people to play for an hour or so, but they found people play much longer - with Salmon Run, Nintendo considered how to implement a co-op oriented mode in a player - versus - player type of game - the devs will monitor how users are playing this mode to see if there's some tweaks they can throw in - more Salmon Run maps will be added in the future, but Nintendo wouldn't comment on adding more enemy types to the mode - rewards are changed each time Salmon Run is played - you can obtain rewards when playing locally, but not gear - originally Nintendo had an idea for this mode, but had no background setting, enemy designs, etc. - Inoue suggested that it should be salmon - themed - when Nintendo hosted the Splatfest that pit Callie against Marie, the development of Splatoon 2 had started - the devs had already decided to have the result reflected in the sequel - they even had an idea to announce the Splatfest with a phrase «Your choice will change the next Splatoon» - the timing to announce a sequel wasn't right, so they decided against this - they eventually released a series of short stories about the Squid Sisters to show how the Splatfest affected the sequel's story - Nintendo wouldn't say if Marina is an Octoling, and noted that Inklings are not paying attention to this too much - Inklings don't care about appearances, as long as everyone is doing something fresh - the Squid Sisters had composers who produced their songs, but Off the Hook are composing their music by themselves - Pearl is genius artist, but she couldn't find a right partner because she's a bit too edgy - she eventually found Marina as a partner though, and their chemistry is sparkling right now - Nintendo is planning a year of content updates for Splatoon 2 - when finished, the quantity of stages will be more than the original - some of the additional stages are totally new and some will be arranged stages from the first game - not all original stages will return and they are choosing stages based on the potential for them to be improved - Brella is shotgun-esque weapon, so the ink hits your opponent more if you are closer - it can shield damage when you open it, but the amount of damage has a limit and once it reaches it, it breaks - you can shoot ink, but you can't use the shield feature when it breaks - the shield won't prevent your allies ink - there are more new weapon categories which haven't been revealed yet - there are no other ranked modes outside of the three current options - the future holds any sort of possibility, but the devs didn't get specific about adding more content like that - for the modes, they adjusted the rule designs so that players will experience the more interesting aspects

Now we have a couple of mechanisms that seem realistic for several specific types of changes such as the cloud height feedback, and we have some observational confirmation of a general latitudinal pattern of feedbacks that many models seem to get, more so than was the case a decade ago.

The paper is meant to invite further research into the mechanisms so that we can determine whether these impacts are driven by specific pollutants in the air or water, by light or sound pollution, or other changes that may have happened to these communities, some of which could be unrelated to gas development.

There are also papers explaining the mechanisms by which specific solar cycle changes could reduce planetary cloud cover and there is observational evidence that shows sub cycles of warming and cooling with the sub cycles correlating to the specific solar mechanisms during the 20 year period at which time there was satellite measurement of planetary cloud cover.

For instance the European beech tree has good overall climate research data, with high data quality for mechanisms of environment, physiology, demography and species interaction, but omissions (medium quality) for specific data about beech tree evolution and dispersal changes under climate change.

This analytical report provides a synoptic overview of the various issues relating to climate change abatement initiatives with specific reference to the issues, challenges and opportunities for the effective implementation of the Clean Development Mechanism (CDM) in countries of Asia and the Pacific.

In Spain, the learning has been somehow painful given the financial implications in the operators following the reduction of the remuneration initially committed by the Kingdom of Spain vis - à - vis the investors, but has shown a way to structure investments in the renewables industry, so to minimise the potential impact of regulatory changes, particularly by entering into power purchase agreements or other mechanisms, evidencing that there is a specific commitment vis - à - vis the relevant investor.

Miners, which compete to add new transaction blocks to the network, can already change their own block gas limits, but in this specific case, the mechanism allows for a form of miner - based voting to be held on ethereum.

Both her clinical work and research focus on mindfulness - based interventions for relapse prevention, with a specific focus on mechanisms of change, including negative affect, thought suppression and craving.

Having a strong theory base and having a clearly articulated model of the predicted mechanism of change are also likely to make interventions effective, as is targeting: aiming interventions at specific populations or individuals deemed to be at risk for parenting difficulties.

However, the evidence that is currently available about the impact of infant massage is poor, and many studies are being conducted without addressing the biological plausibility of the outcomes being measured, the mechanisms by which change might be achieved, or indeed, the need for specific outcomes in population samples.

That is, authors should describe clinical vignettes highlighting key interventions and mechanisms of change regarding their specific approach to treatment in the context of empirical scales.

Verbatim clinical vignettes with several patient and therapist turns highlighting key interventions and mechanisms of change regarding the specific approach to treatment should be provided.