«If you're looking for
very specific molecular targets or pathways in the brain, and how drugs might act on them, the difference between human cells and mouse cells is significant.»
The more that is known about defects in specific pathways in specific cancer types, the
more specific molecular targets — pathway components — appear in the sights of researchers trying to disable or enhance a given pathway.
A better strategy, Watts and colleagues reasoned, might be to target BACE1 with antibodies, immune system sharpshooters that can be designed to attack
very specific molecular targets.
Identifying these T cells»
specific molecular targets, called epitopes, is the next step in developing a vaccine.
If the RNAP ribozyme successfully created a new RNA, the new strand would signal that by binding to
a specific molecular target in its vial.
The UAB group also found that
a specific molecular target, the SK family of ion channels, was involved in the enhanced excitability.
The initial application of various NPs was based on passive targeting [15 - 17], which did not allow the NPs to recognize
their specific molecular targets and resulted in the low selectivity of NP - based methods and also in potentially toxic loads of NPs.
Dr. Maria DeRosa's research examines a type of nucleic acid called «aptamers» that can fold into 3D nanoscale shapes capable of binding tightly to
a specific molecular target.